| COD | Workload | Description |
| 73163-03 | 45 | This course will, among other things, address the following topics: Introduction of Bioinformatics as an interdisciplinary science; introduction to the concepts of technological singularity; elementary algorithms; introduction to the concepts of programming; installation of Python; the use of an integrated environment of development; implementation of equations on Python; programming strategies; relevant concepts of Molecular Biology for Bioinformatics; string manipulation; design of string manipulation software; reading and writing of files on Python; flow control; quest for sequential motives; biological databases GenBank; Protein Data Bank; BioPython; object-oriented programming; regular expressions; discussion of research projects in Bioinformatics. |
| No offer for current semester |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 19515-01 | 15 | Study and discussion of current issues in biosciences, which have outstanding scientific, technological and/or social relevance. Understanding of selected topics through reading and discussing scientific papers and/or conducting experiments. |
| No offer for current semester |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 19516-01 | 15 | Study and discussion of current issues in biosciences, which have outstanding scientific, technological and/or social relevance. Understanding of selected topics through reading and discussing scientific papers and/or conducting experiments. |
| No offer for current semester |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 19517-02 | 30 | Study and discussion of current issues in biosciences, which have outstanding scientific, technological and/or social relevance. Understanding of selected topics through reading and discussing scientific papers and/or conducting experiments. |
| No offer for current semester |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 196EJ-01 | 15 | Study and discussion of current issues in biosciences, which have outstanding scientific, technological and/or social relevance. Understanding of selected topics through reading and discussing scientific papers and/or conducting experiments. |
| No offer for current semester |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 196EK-01 | 15 | Study and discussion of current issues in biosciences, which have outstanding scientific, technological and/or social relevance. Understanding of selected topics through reading and discussing scientific papers and/or conducting experiments. |
| No offer for current semester |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 196J3-02 | 30 | This course aims to train postgraduate students in relation to advances in knowledge in the biology of eukaryotic cells, including sources of information and the critical capacity to evaluate potential applications. |
| Professors | Home time | Lattes |
| LEANDRO VIEIRA ASTARITA | 24 years and 4 months | Link |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Required |
| Cellular and Molecular Biology | Doctorate | Required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 19504-04 | 60 | Big bang theory; origin of the solar system; origin of life; molecular scenarios for the origin of life; Miller experiment; prebiotic peptides; computer simulation of prebiotic peptides; RNA world; habitable zones in the solar system; extreme environments; Mars and life; space probes; icy bodies in the solar system and beyond; detection of exoplanets; the nature of exoplanets; extraterrestrial intelligence; search for extraterrestrial intelligence; SETI project; Drake equation; Seager equation; presentation of technological singularity and its relation with extraterrestrial intelligence; research projects in Astrobiology. |
| No offer for current semester |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 73164-02 | 30 | This course will address the study of the structure and operation of the main biological compounds in the context of physiological and pathological processes. |
| Professors | Home time | Lattes |
| CARLA DENISE BONAN | 25 years and 9 months | Link |
| Concentration area | Type | Required |
| Biochemical and Molecular Pharmacology | Master's | Not required |
| Biochemical and Molecular Pharmacology | Doctorate | Not required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Medical Practice | Master's | Not required |
| Medical Practice | Doctorate | Not required |
| Nephrology | Master's | Not required |
| Nephrology | Doctorate | Not required |
| Neurosciences | Master's | Not required |
| Neurosciences | Doctorate | Not required |
| Surgical Practice | Master's | Not required |
| Surgical Practice | Doctorate | Not required |
| Research line | Description |
| Evaluation of mechanisms involved in inflammatory and nociceptive alterations | This line of research is concerned with the evaluation of mechanisms involved in inflammatory and nociceptive alterations |
| Drug Development | This line of research has been designed for the development of drugs against neglected tropical diseases (tuberculosis and malaria) and the development of drugs against chronic and degenerative diseases. |
| Evaluation of pharmacological targets in cancer treatment | This line of research is concerned with the evaluation of pharmacological targets in cancer treatment and inflammation. |
| Analysis and evaluation of neurochemical and pharmacological mechanisms in neurological diseases | Study of the neurochemical roots and pharmacological targets in neurological diseases. |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| Extra-renal dialysis and transplatation | This line of research is intended for the study of different modalities of renal replacement therapies, with emphasis on organ transplantation, especially when it comes to immunology of transplants. |
| Clinical nephrology and arterial hypertension | This line of research will address topics related to several aspects of clinical nephrology, renal function, arterial hypertension, renal and metabolic diseases. |
| Molecular Biology, immunology and stem cell | This line of research is concerned with the study of molecular alterations in tumors, mainly those affecting the digestive and respiratory systems, through PCR techniques in real time, immunohistochemistry, flow cytometry and cell cultivation. It will also look at Cell Therapy and Tissue Engineering. |
| Cardiology/Risk Factors and genetics factors in cardiovascular diseases | This line of research is concerned with assessing risk factors for cardiovascular surgeries using markers; traditional risk factors (dyslipidemias, arterial hypertension, diabetes, smoke addiction) and potential emerging ones (apolipoprotein B,small and dense LDL cholesterol) in coronary heart diseases. |
| Cardiology/Cellular therapy | This line of research is intended to assess the efficiency and safety of autologous implants of bone marrow stem cells in patients suffering from dilated cardiomyopathy and in patients suffering from acute myocardial infarction. |
| Cellular metabolism and membrane transport in renal and metabolic diseases (or disease states) | This line of research is designed for the study of physiopathogenic mechanisms of several renal and metabolic diseases. |
| Training and Faculty Development in Health | |
| Study abdomen adult and elderly healthy and sick with new technologies in Diagnostic Imaging | First of all, this line of research is intended to introduce students to different abdominal organs in advanced imaging modalities, such as magnetic resonance and positron emission tomography. It is intended to study the normal anatomy of these organs and tissues and their anatomic variations, thus allowing for a comparison between healthy and unhealthy individuals. With this, we intent to provide deeper insights into the abdomen's normal anatomy and its anatomic variation through new imaging technologies. Additionally, this line of research will determine the diagnostic imaging accuracy of gastrointestinal tract and urinary system diseases. We are intent on reaching an earlier and more precise diagnosis of the diseases of adult and elderly patients, thus increasing their survival. It has been designed to produce researchers and professors who want to work within this line of research responsible for studying the most common diseases in our population. |
| Clinical Epidemiology | This area of concentration is intended to develop research in clinical epidemiology focusing on its methodological and clinical aspects. This line of research intends to encourage the development of research projects that contribute to the progress in identification, intervention and promotion of determinants of the health-disease process in human population. |
| Functional and Molecular Image of the Body | Functional imaging is the state-of-the-art in diagnostic imaging. Magnetic Resonance made a giant leap in that direction through the employment of ultra-rapid acquisition techniques, which have enabled the measurement of variations in oxygen consumption levels arising from the BOLD effect and an estimation of the cellularity of tissues through the diffusion technique. PET has enabled Nuclear Medicine to measure the level of consumption of glucose in the tissue, by making use of ionizing radiation. It is largely employed in the investigation of tumors and metastasis, which have naturally increased the consumption of glucose due to a larger metabolic level. More recently, the Dynamic PET has enabled the assessment of the consumption of glucose over time and the measurement of the most active regions more precisely. |
| Epidemiology and Environmental Health | This course is intended to encourage the development of research into the area of epidemiology and environmental health with an eye to the methodological and clinical aspects. This line of research seeks to encourage the development of research projects that contribute to the advancement of the identification, intervention and promotion of the determinants of the health-disease process in human population. |
| Technological Innovations in the Health Area | Curently, we are seeing worldwide the fast development of technologies, proceedings and medicines focus at the most effective treatment of diseases and the restoration of health. This accelerated step with which medical knowledge progresses makes it necessary to create a new mentality in medical training, stimulating curiosity, the active search for knowledge and constant updating. The number and complexity of the scientific processes that lead to this evolution are also worthy of attention, both due to the need for training to understand them, as well as the work opportunity they represent for doctors in general. |
| Neurology/ stem cells | This line of research is concerned with the assessment of the possibility of regeneration of central and peripheral neurological injuries resulting from neurodegenerative diseases, with somatic stem cells, as well as with the study of the structural and functional mechanisms of regeneration from injuries. |
| Behavioral neurology and neuropsychiatry | This line of research will look at the neurobiology of psychiatric diseases and behavioral alterations in major neurological diseases. |
| Cognitive brain imaging | This line of research will look at the development of new techniques for the analysis of neuroimaging and studies of neural bases of superior cognitive processes (for instance, language comprehension and acquisition, executive functions, spatial reasoning). |
| Neurotoxic activity of ureases and derived peptides | This line of research will address the neurotoxic and pro-inflammatory activities of ureases of different organisms. It will also address the methodologies of study of neurotoxicity relying on the use of insects-models. As well as this, it will look at ureases as virulence factors for pathogenic microorganisms, especially bacteria Helicobacter pylori and Proteus mirabilis and Cryptococcu yeasts. |
| Neuroinflammation/Multiple Sclerosis/ neuromyelitis optica | The inflammation resulting from neurological diseases may be primarily involved with the physiopathology of immunomediated diseases of the nervous system, such as multiple sclerosis, neuromyelitis optica, ADEM - acute demyelinating encephalomyelitis, Guillain-Barré syndrome, autoimmune encephalitis and some neurological complications resulting directly or indirectly from viral or bacterial infections (e.g. meningoencephalitis). In other diseases, the inflammation plays a major role, but less clear than it is in strokes and in degenerative diseases of the central nervous system. The deregulation in the immune system, be it either temporary or permanent, may lead to injuries in the brain, bone marrow and peripheral nerves that cause permanent neuronal damage with the risk of aftereffects and permanent incapacity. By relying on advanced methods in molecular biology associated with clinical and imaging assessment (magnetic resonance, nuclear medicine), we have conducted research that is intended to understand the intrinsic and extrinsic mechanisms that lead to an increase of pro-inflammatory substances such as cytokines, chemokines, the production of autoantibodies, complement system activation, proliferation / maturation of autoreactive lymphocytes T and B, microglial activation and the alteration of the blood-brain barrier. Besides, we have conducted research for the identification of specific biomarkers for each disease which may assist in the establishment of better diagnosis/prognosis and in experimental animal models for the study of physiopathology and innovative therapeutic interventions. |
| Epilepsy | This line of research will cover clinical and electroencephalographic, pharmacological, neuroimaging and surgical studies in the realm of epilepsy. The direct involvement of São Lucas Hospital with the diagnosis, clinical treatment and epilepsy surgery opens interesting perspectives of investigation, seeking diagnostic refinement, new treatment options and the correlations of epileptic syndromes with structural alterations of the brain. |
| The central nervous system (CNS) formation stages can be considered a great concert with the regency of different signaling molecules that trigger a cascade of dependent and complementary processes until the formation of all CNS structures as well as their different functionalities. The human brain is a puzzle of more than 100 billion pieces that must be accurately directed to its unique and specific location. The studies of Molecurar Bases of Embryonic Neurogenesis presents a comprehensive view of understanding the CNS, from its embryonic formation to neurogenesis in the adult brain, guiding clinical and pathological situations related to cerebral malformations and new therapeutic alternatives for CNS recovery. The use of molecular techniques as next-generation sequencing (NGS), super arrays, relative expression, genotyping, etc., are used to describe signaling pathways, genesis of pathologies, and application of precision medicine for the treatment of various diseases. The cell reprogramming at the embryonic level through the generation of induced pluripotent stem cells (iPSC) helps to understand embryonic neurogenesis and screening of new drugs for the treatment of alterations during the formation of the central nervous system and its associated pathologies | |
| Artificial Intelligence in Healthcare | Fluency in oral reading is a crucial skill for children and adolescents, involving the ability to read a text with accuracy, appropriate expression, and at a determined pace. Artificial intelligence has enabled considerable advances in activities that previously required time and attention from specialized professionals, also offering the advantage of impartial evaluation. Moreover, a significant portion of students in Brazil presents literacy difficulties associated with reading skills and lacks adequate assistance and diagnosis for conditions such as dyslexia. This research line aims to encompass research projects at the intersection of health, education, and artificial intelligence. The studies seek to investigate tools for assessing oral reading through innovative technologies, which can be used by health professionals in collaboration with educators. These tools aim to assist in identifying the level of reading development, factors influencing these skills, association with academic performance, early screening of signs of difficulties and disorders affecting reading fluency, differential diagnoses, as well as the appropriate medical/educational conduct. |
| Obesity and Metabolic Syndrome | This line is concerned with research in the area of obesity and metabolic syndrome with consequences in co-morbidities involved or related to the aforementioned pathologies. |
| Epidemiological, Clinicopathological, Radiological and Molecular aspects of malignant neoplasms. | This area of concentration is intended to describe patients who suffer from malignant neoplasms in their different clinical stages, as well as to assess their clinical outcome by looking at the clinical, histopathological, radiological and molecular variables. Studies in this area may be accountable for addressing some issues that are still controversial among the scientific community. |
| Videolaparoscopic Surgery | This area of concentration is intended to assess the advantages of the procedures conducted using less invasive techniques. |
| COD | Workload | Description |
| 73140-03 | 45 | This course is intended to analyze the several levels of organization of the nervous system by integrating cellular and molecular aspects with sensory, motor and superior functions. |
| No offer for current semester |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 73157-02 | 30 | This course is intended to provide students with deeper and new insights into the relevant aspects of biology of tumors, from development to therapies. |
| No offer for current semester |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 73161-03 | 45 | To follow is a list of topics this course will look at: Characteristics of plant cells. The correlation between the plant's cellular/molecular mechanisms with strategic ones to different biotic agents of stress. Biotechnological strategies to minimize biotic stresses. The topics will be delivered in the form of lectures. |
| No offer for current semester |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Ecology and Evolution of Biodiversity | Master's | Not required |
| Ecology and Evolution of Biodiversity | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| Ecology and Conservation | This line of research encompasses projects focusing on ecological relationships among organisms and with their environment, including studies of autecology, ecophysiology, behavior, population dynamics and community ecology, as well as projects aiming to provide scientific bases for biodiversity conservation strategies. |
| Systematics and Evolution | The research line brings together projects related to the evolution of biodiversity, including studies in phylogenetic systematics (using morphological and molecular data, including phylogenomics), taxonomy, comparative morphology, biogeography, evolutionary genetics, and comparative genomics. |
| The research line brings together projects focused on the use of large amounts of information ('big data') and the development of innovative data mining and analysis methodologies (e.g., employing machine learning) to investigate issues related to the characterization, monitoring, and conservation of biodiversity | |
| The research line encompasses projects aimed at applying ecological data, biodiversity component analyses, and/or interdisciplinary studies to solve problems with more direct socio-environmental and/or economic impact. This includes studies in the fields of ecotoxicology and environmental microbiology with a focus on the characterization, monitoring, and mitigation of environmental impacts, as well as the development of more sustainable agricultural methods using components of Brazil's native biodiversity. It also includes projects aimed at developing innovative products from biodiversity sources and/or integrating biodiversity analyses into regional economic development models with a focus on environmental sustainability. |
| COD | Workload | Description |
| 73196-02 | 30 | The topics this course addresses are as follows: Comparative analysis of genomes, with focus on nuclear genomes of eukaryotes; Comparative mapping of genomes; Structure of genomes and its functional consequences; Genomic architecture and variation in the number of copies of genomic segments; Evolution of the structure of genomes in different bodies; Current methods for sequencing, assembling and annotation of eukaryotic genomes; Evolutionary analysis involving genomic scale data; phylogenomics and population genomics. |
| No offer for current semester |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Ecology and Evolution of Biodiversity | Master's | Not required |
| Ecology and Evolution of Biodiversity | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| Ecology and Conservation | This line of research encompasses projects focusing on ecological relationships among organisms and with their environment, including studies of autecology, ecophysiology, behavior, population dynamics and community ecology, as well as projects aiming to provide scientific bases for biodiversity conservation strategies. |
| Systematics and Evolution | The research line brings together projects related to the evolution of biodiversity, including studies in phylogenetic systematics (using morphological and molecular data, including phylogenomics), taxonomy, comparative morphology, biogeography, evolutionary genetics, and comparative genomics. |
| The research line brings together projects focused on the use of large amounts of information ('big data') and the development of innovative data mining and analysis methodologies (e.g., employing machine learning) to investigate issues related to the characterization, monitoring, and conservation of biodiversity | |
| The research line encompasses projects aimed at applying ecological data, biodiversity component analyses, and/or interdisciplinary studies to solve problems with more direct socio-environmental and/or economic impact. This includes studies in the fields of ecotoxicology and environmental microbiology with a focus on the characterization, monitoring, and mitigation of environmental impacts, as well as the development of more sustainable agricultural methods using components of Brazil's native biodiversity. It also includes projects aimed at developing innovative products from biodiversity sources and/or integrating biodiversity analyses into regional economic development models with a focus on environmental sustainability. |
| COD | Workload | Description |
| 7311C-04 | 60 | The topics this course addresses are as follows: Introduction to computational molecular biophysics; Molecular models; Computer-simulated methods; Theoretical foundations of the molecular dynamics method; Forms of potential functions; Harmonic and torsional geometric potentials; Van de Waals force; Eletrostactics; Methods of optimization of molecular geometries; Implicit and explicit solvent molecular dynamics simulations; Production of dynamics trajectories; Dynamics of polypeptides and proteins; Analysis of local and global conformational changes in polypeptides and proteins; Data science applied to computational simulations; Applications of computational molecular biophysics; Micro-protein folding. |
| No offer for current semester |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 83293-02 | 30 | The purpose of this course is to introduce the essential aspects of statistics and their applications in dental research. It will promote the understanding of the elements of statistical inference and to help identify and choose the main basic statistical procedures that occur in practice. It will also present the justification for the calculation of sample size in different dental research situations. |
| Professors | Home time | Lattes |
| HELIO RADKE BITTENCOURT | 22 years and 4 months | Link |
| Concentration area | Type | Required |
| Biochemical and Molecular Pharmacology | Master's | Not required |
| Biochemical and Molecular Pharmacology | Doctorate | Not required |
| Biology and Orofacial Rehabilitation | Master's | Not required |
| Biology and Orofacial Rehabilitation | Doctorate | Not required |
| Biomedical Gerontology | Master's | Not required |
| Biomedical Gerontology | Doctorate | Not required |
| CTBMF | Master's | Not required |
| CTBMF | Doctorate | Not required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Clinical Psychology | Master's | Not required |
| Clinical Psychology | Doctorate | Not required |
| Clinical Stomatology | Master's | Not required |
| Clinical Stomatology | Doctorate | Not required |
| Dental Materials | Master's | Not required |
| Dental Materials | Doctorate | Not required |
| Dental Prosthetics | Master's | Not required |
| Dental Prosthetics | Doctorate | Not required |
| Endodontics | Master's | Not required |
| Endodontics | Doctorate | Not required |
| Human Cognition | Master's | Not required |
| Human Cognition | Doctorate | Not required |
| Medical Practice | Master's | Not required |
| Medical Practice | Doctorate | Not required |
| Nephrology | Master's | Not required |
| Nephrology | Doctorate | Not required |
| Neurosciences | Master's | Not required |
| Neurosciences | Doctorate | Not required |
| Ontological Clinic | Master's | Not required |
| Ontological Clinic | Doctorate | Not required |
| Orthodontics and Facial Orthopedics | Master's | Not required |
| Orthodontics and Facial Orthopedics | Doctorate | Not required |
| Pediatrics | Master's | Not required |
| Pediatrics | Doctorate | Not required |
| Psychology | Doctorate | Not required |
| Restorative Dentistry | Master's | Not required |
| Restorative Dentistry | Doctorate | Not required |
| Social Psychology | Master's | Not required |
| Social Psychology | Doctorate | Not required |
| Surgical Practice | Master's | Not required |
| Surgical Practice | Doctorate | Not required |
| oral biology | Master's | Not required |
| oral biology | Doctorate | Not required |
| Research line | Description |
| Evaluation of mechanisms involved in inflammatory and nociceptive alterations | This line of research is concerned with the evaluation of mechanisms involved in inflammatory and nociceptive alterations |
| Drug Development | This line of research has been designed for the development of drugs against neglected tropical diseases (tuberculosis and malaria) and the development of drugs against chronic and degenerative diseases. |
| Evaluation of pharmacological targets in cancer treatment | This line of research is concerned with the evaluation of pharmacological targets in cancer treatment and inflammation. |
| Analysis and evaluation of neurochemical and pharmacological mechanisms in neurological diseases | Study of the neurochemical roots and pharmacological targets in neurological diseases. |
| Biological Aspects of Aging | This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo). |
| Clinical and Emotional Aspects of Aging | This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition. |
| Social-cultural, Demographic and Bioethical Aspects of Aging | This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging. |
| Aging and Public Health | This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life. |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| Extra-renal dialysis and transplatation | This line of research is intended for the study of different modalities of renal replacement therapies, with emphasis on organ transplantation, especially when it comes to immunology of transplants. |
| Clinical nephrology and arterial hypertension | This line of research will address topics related to several aspects of clinical nephrology, renal function, arterial hypertension, renal and metabolic diseases. |
| Molecular Biology, immunology and stem cell | This line of research is concerned with the study of molecular alterations in tumors, mainly those affecting the digestive and respiratory systems, through PCR techniques in real time, immunohistochemistry, flow cytometry and cell cultivation. It will also look at Cell Therapy and Tissue Engineering. |
| Cardiology/Risk Factors and genetics factors in cardiovascular diseases | This line of research is concerned with assessing risk factors for cardiovascular surgeries using markers; traditional risk factors (dyslipidemias, arterial hypertension, diabetes, smoke addiction) and potential emerging ones (apolipoprotein B,small and dense LDL cholesterol) in coronary heart diseases. |
| Cardiology/Cellular therapy | This line of research is intended to assess the efficiency and safety of autologous implants of bone marrow stem cells in patients suffering from dilated cardiomyopathy and in patients suffering from acute myocardial infarction. |
| Cellular metabolism and membrane transport in renal and metabolic diseases (or disease states) | This line of research is designed for the study of physiopathogenic mechanisms of several renal and metabolic diseases. |
| Training and Faculty Development in Health | |
| Study abdomen adult and elderly healthy and sick with new technologies in Diagnostic Imaging | First of all, this line of research is intended to introduce students to different abdominal organs in advanced imaging modalities, such as magnetic resonance and positron emission tomography. It is intended to study the normal anatomy of these organs and tissues and their anatomic variations, thus allowing for a comparison between healthy and unhealthy individuals. With this, we intent to provide deeper insights into the abdomen's normal anatomy and its anatomic variation through new imaging technologies. Additionally, this line of research will determine the diagnostic imaging accuracy of gastrointestinal tract and urinary system diseases. We are intent on reaching an earlier and more precise diagnosis of the diseases of adult and elderly patients, thus increasing their survival. It has been designed to produce researchers and professors who want to work within this line of research responsible for studying the most common diseases in our population. |
| Clinical Epidemiology | This area of concentration is intended to develop research in clinical epidemiology focusing on its methodological and clinical aspects. This line of research intends to encourage the development of research projects that contribute to the progress in identification, intervention and promotion of determinants of the health-disease process in human population. |
| Functional and Molecular Image of the Body | Functional imaging is the state-of-the-art in diagnostic imaging. Magnetic Resonance made a giant leap in that direction through the employment of ultra-rapid acquisition techniques, which have enabled the measurement of variations in oxygen consumption levels arising from the BOLD effect and an estimation of the cellularity of tissues through the diffusion technique. PET has enabled Nuclear Medicine to measure the level of consumption of glucose in the tissue, by making use of ionizing radiation. It is largely employed in the investigation of tumors and metastasis, which have naturally increased the consumption of glucose due to a larger metabolic level. More recently, the Dynamic PET has enabled the assessment of the consumption of glucose over time and the measurement of the most active regions more precisely. |
| Epidemiology and Environmental Health | This course is intended to encourage the development of research into the area of epidemiology and environmental health with an eye to the methodological and clinical aspects. This line of research seeks to encourage the development of research projects that contribute to the advancement of the identification, intervention and promotion of the determinants of the health-disease process in human population. |
| Technological Innovations in the Health Area | Curently, we are seeing worldwide the fast development of technologies, proceedings and medicines focus at the most effective treatment of diseases and the restoration of health. This accelerated step with which medical knowledge progresses makes it necessary to create a new mentality in medical training, stimulating curiosity, the active search for knowledge and constant updating. The number and complexity of the scientific processes that lead to this evolution are also worthy of attention, both due to the need for training to understand them, as well as the work opportunity they represent for doctors in general. |
| Neurology/ stem cells | This line of research is concerned with the assessment of the possibility of regeneration of central and peripheral neurological injuries resulting from neurodegenerative diseases, with somatic stem cells, as well as with the study of the structural and functional mechanisms of regeneration from injuries. |
| Behavioral neurology and neuropsychiatry | This line of research will look at the neurobiology of psychiatric diseases and behavioral alterations in major neurological diseases. |
| Cognitive brain imaging | This line of research will look at the development of new techniques for the analysis of neuroimaging and studies of neural bases of superior cognitive processes (for instance, language comprehension and acquisition, executive functions, spatial reasoning). |
| Neurotoxic activity of ureases and derived peptides | This line of research will address the neurotoxic and pro-inflammatory activities of ureases of different organisms. It will also address the methodologies of study of neurotoxicity relying on the use of insects-models. As well as this, it will look at ureases as virulence factors for pathogenic microorganisms, especially bacteria Helicobacter pylori and Proteus mirabilis and Cryptococcu yeasts. |
| Neuroinflammation/Multiple Sclerosis/ neuromyelitis optica | The inflammation resulting from neurological diseases may be primarily involved with the physiopathology of immunomediated diseases of the nervous system, such as multiple sclerosis, neuromyelitis optica, ADEM - acute demyelinating encephalomyelitis, Guillain-Barré syndrome, autoimmune encephalitis and some neurological complications resulting directly or indirectly from viral or bacterial infections (e.g. meningoencephalitis). In other diseases, the inflammation plays a major role, but less clear than it is in strokes and in degenerative diseases of the central nervous system. The deregulation in the immune system, be it either temporary or permanent, may lead to injuries in the brain, bone marrow and peripheral nerves that cause permanent neuronal damage with the risk of aftereffects and permanent incapacity. By relying on advanced methods in molecular biology associated with clinical and imaging assessment (magnetic resonance, nuclear medicine), we have conducted research that is intended to understand the intrinsic and extrinsic mechanisms that lead to an increase of pro-inflammatory substances such as cytokines, chemokines, the production of autoantibodies, complement system activation, proliferation / maturation of autoreactive lymphocytes T and B, microglial activation and the alteration of the blood-brain barrier. Besides, we have conducted research for the identification of specific biomarkers for each disease which may assist in the establishment of better diagnosis/prognosis and in experimental animal models for the study of physiopathology and innovative therapeutic interventions. |
| Epilepsy | This line of research will cover clinical and electroencephalographic, pharmacological, neuroimaging and surgical studies in the realm of epilepsy. The direct involvement of São Lucas Hospital with the diagnosis, clinical treatment and epilepsy surgery opens interesting perspectives of investigation, seeking diagnostic refinement, new treatment options and the correlations of epileptic syndromes with structural alterations of the brain. |
| The central nervous system (CNS) formation stages can be considered a great concert with the regency of different signaling molecules that trigger a cascade of dependent and complementary processes until the formation of all CNS structures as well as their different functionalities. The human brain is a puzzle of more than 100 billion pieces that must be accurately directed to its unique and specific location. The studies of Molecurar Bases of Embryonic Neurogenesis presents a comprehensive view of understanding the CNS, from its embryonic formation to neurogenesis in the adult brain, guiding clinical and pathological situations related to cerebral malformations and new therapeutic alternatives for CNS recovery. The use of molecular techniques as next-generation sequencing (NGS), super arrays, relative expression, genotyping, etc., are used to describe signaling pathways, genesis of pathologies, and application of precision medicine for the treatment of various diseases. The cell reprogramming at the embryonic level through the generation of induced pluripotent stem cells (iPSC) helps to understand embryonic neurogenesis and screening of new drugs for the treatment of alterations during the formation of the central nervous system and its associated pathologies | |
| Artificial Intelligence in Healthcare | Fluency in oral reading is a crucial skill for children and adolescents, involving the ability to read a text with accuracy, appropriate expression, and at a determined pace. Artificial intelligence has enabled considerable advances in activities that previously required time and attention from specialized professionals, also offering the advantage of impartial evaluation. Moreover, a significant portion of students in Brazil presents literacy difficulties associated with reading skills and lacks adequate assistance and diagnosis for conditions such as dyslexia. This research line aims to encompass research projects at the intersection of health, education, and artificial intelligence. The studies seek to investigate tools for assessing oral reading through innovative technologies, which can be used by health professionals in collaboration with educators. These tools aim to assist in identifying the level of reading development, factors influencing these skills, association with academic performance, early screening of signs of difficulties and disorders affecting reading fluency, differential diagnoses, as well as the appropriate medical/educational conduct. |
| Etiopathogenesis and Treatment of Periodontal and Periapical Diseases | This line of research aims to study the mechanisms involved in periapical and periodontal alterations, aiming to analyze their relationship with systemic diseases, as well as to identify new treatment strategies for these conditions. |
| Etiopathogenesis and Treatment in Stomatology | The objectives of this line of research involve the evaluation of the pathophysiology of diseases affecting the oral mucosa and salivary glands, including oral cancer, focusing on the clinical, immunological, and pathological aspects of these conditions, in order to identify new forms of prevention and treatment of such diseases. |
| Pediatric Oral Health | This line of research aims to evaluate new approaches to the prevention, diagnosis, and treatment of oral cavity disorders, focusing on the management of pediatric patients. |
| Restorative and Reconstructive Dentistry | This line of research focuses on developing new technologies and approaches aimed at aesthetic and functional oral rehabilitation, using laboratory and clinical assessment methodologies. It also includes new approaches for the orthodontic, orthopedic, and surgical correction of orofacial deformities, seeking to improve the diagnosis and management of patients with these conditions. |
| Assessment and psychological interventions in mental health | This line of research concentrates studies related to mental health outcomes based on different theories and methods in Clinical Psychology. It aims at understanding psychological processes and building and adapting instruments and interventions with a psychotherapeutic and psychoeducational focus. |
| Psychosocial Processes: Practices and contexts | This line of research concentrates studies on psychosocial phenomena and vulnerability processes in different contexts, such as education, public health, work, politics and justice. It aims to develop strategies for assessment and intervention with individuals, groups and organizations based on theoretical-methodological approaches that articulate different perspectives from Social Psychology and other fields of knowledge. |
| Cognition, brain and behavior | This line of research focuses on basic and applied studies of cognition and its behavioral and neurobiological implications. We seek to investigate neurocognitive and psychobiological processes and their relationship with behavior, development, learning and mental health. Research approaches involve theoretical and experimental models and instruments from neuropsychology, neurobiology and neuroscience. |
| Well-being, health and quality of life | This line of research concentrates studies that use an interdisciplinary approach on the relationship between mental health and lifestyle, understood as the set of behaviors related to food, physical activity, sleep, spirituality, financial well-being, well-being occupational and social relationships. The line aims at building basic and applied knowledge for evaluation and intervention in the prevention and promotion of quality of life and its different domains. |
| Obesity and Metabolic Syndrome | This line is concerned with research in the area of obesity and metabolic syndrome with consequences in co-morbidities involved or related to the aforementioned pathologies. |
| Epidemiological, Clinicopathological, Radiological and Molecular aspects of malignant neoplasms. | This area of concentration is intended to describe patients who suffer from malignant neoplasms in their different clinical stages, as well as to assess their clinical outcome by looking at the clinical, histopathological, radiological and molecular variables. Studies in this area may be accountable for addressing some issues that are still controversial among the scientific community. |
| Videolaparoscopic Surgery | This area of concentration is intended to assess the advantages of the procedures conducted using less invasive techniques. |
| Biomechanics, Pain and Orofacial Dysfunction | This line of research is aimed to analyze the pathophysiology of orofacial pain, temporomandibular dysfunction, bruxism and parafunctional habits, focusing on the biomechanical characterization of the stomatognathic system and its reflexes on the organism, seeking to identify new diagnostic and therapeutic strategies for these conditions. |
| Biomaterials and Tissue Engineering | This line of research aims at the development and evaluation of the efficacy and safety of new dental materials, as well as innovative tissue engineering strategies, focusing on tissue regeneration and the reduction of infectious oral complications. |
| Microbiology and Oral Immunology | This line of research aims to develop research with a specific focus on oral microbiology and oral immunology, for diagnostic and therapeutic purposes. |
| COD | Workload | Description |
| 196B1-02 | 30 | Protein targets, protein crystallography, how docking programs work, SAnDReS: a computational tool for docking, electrostatic energy in proteinligand complexes, Van der Waals potential in protein complexes, hydrogen bonds in protein-ligand complexes, molecular dynamics simulations with NAMD2, docking with AutoDock4, Molegro Virtual Docker for docking, docking with GemDock, docking with SwissDock, molecular docking simulations with ArgusLab, homology modeling of protein targets with MODELLER, machine learning to predict binding affinity, exploring the scoring function space, projects in drug design with computational approaches. |
| No offer for current semester |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 1968P-02 | 30 | Protein targets in SARS-CoV-2, protein crystallography, how docking programs work, SAnDReS: a computational tool for docking, electrostatic energy in proteinligand complexes, Van der Waals potential in protein complexes, hydrogen bonds in protein-ligand complexes, molecular dynamics simulations with NAMD2, docking with AutoDock4, Molegro Virtual Docker for docking, docking with GemDock, docking with SwissDock, molecular docking simulations with ArgusLab, homology modeling of protein targets with MODELLER, machine learning to predict binding affinity, exploring the scoring function space, projects in drug design with computational approaches. |
| No offer for current semester |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 1968N-04 | 60 | Study and discussion of research topics related to COVID-19 treatment strategies. Search for new anti-SARS-CoV-2 compounds and repurposing of antiviral and immunomodulatory compounds to treat COVID-19. Development of new vacines to prevent contagion with SARS-CoV-2 or other coronaviruses. Comparison of available and development of new diagnostic methods. |
| No offer for current semester |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 19503-02 | 30 | Study of the microbial communities of different ecosystems, addressing their composition, advanced topics on the interactions involving species of prokaryotes, eukaryotes and viruses, as well as survey methods a and their biotechnological potential. |
| No offer for current semester |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Ecology and Evolution of Biodiversity | Master's | Not required |
| Ecology and Evolution of Biodiversity | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| Ecology and Conservation | This line of research encompasses projects focusing on ecological relationships among organisms and with their environment, including studies of autecology, ecophysiology, behavior, population dynamics and community ecology, as well as projects aiming to provide scientific bases for biodiversity conservation strategies. |
| Systematics and Evolution | The research line brings together projects related to the evolution of biodiversity, including studies in phylogenetic systematics (using morphological and molecular data, including phylogenomics), taxonomy, comparative morphology, biogeography, evolutionary genetics, and comparative genomics. |
| The research line brings together projects focused on the use of large amounts of information ('big data') and the development of innovative data mining and analysis methodologies (e.g., employing machine learning) to investigate issues related to the characterization, monitoring, and conservation of biodiversity | |
| The research line encompasses projects aimed at applying ecological data, biodiversity component analyses, and/or interdisciplinary studies to solve problems with more direct socio-environmental and/or economic impact. This includes studies in the fields of ecotoxicology and environmental microbiology with a focus on the characterization, monitoring, and mitigation of environmental impacts, as well as the development of more sustainable agricultural methods using components of Brazil's native biodiversity. It also includes projects aimed at developing innovative products from biodiversity sources and/or integrating biodiversity analyses into regional economic development models with a focus on environmental sustainability. |
| COD | Workload | Description |
| 19513-02 | 30 | Basic and advanced theoretical concepts of flow cytometry. Understanding and functioning of different devices, usual applications such as immunophenotyping, cell cycle, cell death, detection of phosphorylated proteins, quantification of cytokines, mitochondrial function measurements and data analyses. |
| No offer for current semester |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 73165-04 | 60 | This course will focus on the development of abilities and competences for the design, interpretation, discussion and conduction of research into the human genome with an eye to individual molecular identification for its application into forensic investigations. |
| No offer for current semester |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 19501-02 | 30 | The aim of the course is to provide students with basic theoretical and practical concepts of flow cytometry; such as operation and maintenance, applications in common techniques such as immunophenotyping, cell cycle, cell death, detection of phosphorylated proteins, quantification of cytokines, among others. |
| Professors | Home time | Lattes |
| FLORENCIA MARIA BARBE TUANA | 6 years and 8 months | Link |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 73123-04 | 60 | This course is intended to enable students to understand and apply their knowledge of immunology and the different vaccination strategies used up until today. |
| No offer for current semester |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 73138-02 | 30 | This course will address the molecular objects and goals of molecular design, molecular representation, formats used for molecular representation (small molecules and proteins), molecular and functional databases, ligand-protein interaction, molecular and thermodynamic bases of ligand-protein interaction, the empirical scoring function, molecular docking algorithms, virtual screening of drugs, Lipinski's and Veber's rules for the selection of potential drugs, development of anti-HIV drugs, development of anti-cancer drugs, development of anti-bacterial drugs and discussion of projects for the development of structure-based drugs. |
| No offer for current semester |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 196P5-02 | 30 | This discipline consists of the presentation of scientific seminars by researchers, professors or post-graduate students from the different basic and applied areas of Biological Sciences, with emphasis on Cellular and Molecular Biology. After the presentation of the theme, there is a period in which it is desirable that a discussion be held with the participation of the students. GOALS: Provide students with contact with the various research themes within the scope of the PPGBCM, thus promoting the integration of knowledge; Provide students with the opportunity to learn about different areas of relevant scientific research related to Cellular and Molecular Biology through the presentation of seminars by researchers from national and international teaching and research institutions; Develop critical vision skills and participation in scientific discussions. |
| No offer for current semester |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Required |
| Cellular and Molecular Biology | Doctorate | Required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 196P6-02 | 30 | This discipline consists of the presentation of scientific seminars by researchers, professors or post-graduate students from the different basic and applied areas of Biological Sciences, with emphasis on Cellular and Molecular Biology. After the presentation of the theme, there is a period in which it is desirable that a discussion be held with the participation of the students. GOALS: Provide students with contact with the various research themes within the scope of the PPGBCM, thus promoting the integration of knowledge; Provide students with the opportunity to learn about different areas of relevant scientific research related to Cellular and Molecular Biology through the presentation of seminars by researchers from national and international teaching and research institutions; Develop critical vision skills and participation in scientific discussions. |
| Professors | Home time | Lattes |
| ANDRE ARIGONY SOUTO | 26 years and 9 months | Link |
| ELKE BROMBERG | 31 years and 9 months | Link |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Required |
| Cellular and Molecular Biology | Doctorate | Required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 196UB-02 | 30 | General guidelines on intellectual property rights and their practical application in entrepreneurship and technological innovation, with a focus on various fields in cellular and molecular biology research. Analysis of intellectual property protection as a strategy in the planning of research projects. Searching for patents in databases such as Scifinder, Web of Science, Google Patent, WIPO, and Espacenet |
| No offer for current semester |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 19518-04 | 60 | The main goals of this course are to improve students skills associated with writing scientific papers for high-quality journals and those necessary to give oral presentations at scientific meetings. Classes will be based on the discussion of topics related to writing skills, including manuscript structure, goals and writing strategies. Ethical aspects of scientific practices regarding authorship, conflict of interests and data analysis and preparation are also discussed. Key aspects of oral presentation and how to organize and give effective talks will also be discussed. |
| No offer for current semester |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Ecology and Evolution of Biodiversity | Master's | Not required |
| Ecology and Evolution of Biodiversity | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| Ecology and Conservation | This line of research encompasses projects focusing on ecological relationships among organisms and with their environment, including studies of autecology, ecophysiology, behavior, population dynamics and community ecology, as well as projects aiming to provide scientific bases for biodiversity conservation strategies. |
| Systematics and Evolution | The research line brings together projects related to the evolution of biodiversity, including studies in phylogenetic systematics (using morphological and molecular data, including phylogenomics), taxonomy, comparative morphology, biogeography, evolutionary genetics, and comparative genomics. |
| The research line brings together projects focused on the use of large amounts of information ('big data') and the development of innovative data mining and analysis methodologies (e.g., employing machine learning) to investigate issues related to the characterization, monitoring, and conservation of biodiversity | |
| The research line encompasses projects aimed at applying ecological data, biodiversity component analyses, and/or interdisciplinary studies to solve problems with more direct socio-environmental and/or economic impact. This includes studies in the fields of ecotoxicology and environmental microbiology with a focus on the characterization, monitoring, and mitigation of environmental impacts, as well as the development of more sustainable agricultural methods using components of Brazil's native biodiversity. It also includes projects aimed at developing innovative products from biodiversity sources and/or integrating biodiversity analyses into regional economic development models with a focus on environmental sustainability. |
| COD | Workload | Description |
| 196J1-04 | 60 | This course seeks to assist in the construction of knowledge about the main techniques applied to research and used in the laboratory, the use of experimental models as a research tool in different contexts, in addition to the basic foundations of the organization and analysis of data resulting from scientific research. |
| No offer for current semester |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Pediatrics | Master's | Not required |
| Pediatrics | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 73152-04 | 60 | This course will address the aspects related to the analytical technique of mass spectrometry focusing on applications of biological systems. |
| No offer for current semester |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 73191-03 | 45 | To follow is a list of topics this course will address: The metabolic regulation of processes related to plant growth, such as the metabolism of carbohydrates and nitrogen. Metabolic and molecular aspects of the actions of plant hormones. Endocrine signaling in plant growth. Molecular physiology in the production, transport and use of mineral nutrients. Metabolism of growth promotion through biotic interactions. |
| No offer for current semester |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Ecology and Evolution of Biodiversity | Master's | Not required |
| Ecology and Evolution of Biodiversity | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| Ecology and Conservation | This line of research encompasses projects focusing on ecological relationships among organisms and with their environment, including studies of autecology, ecophysiology, behavior, population dynamics and community ecology, as well as projects aiming to provide scientific bases for biodiversity conservation strategies. |
| Systematics and Evolution | The research line brings together projects related to the evolution of biodiversity, including studies in phylogenetic systematics (using morphological and molecular data, including phylogenomics), taxonomy, comparative morphology, biogeography, evolutionary genetics, and comparative genomics. |
| The research line brings together projects focused on the use of large amounts of information ('big data') and the development of innovative data mining and analysis methodologies (e.g., employing machine learning) to investigate issues related to the characterization, monitoring, and conservation of biodiversity | |
| The research line encompasses projects aimed at applying ecological data, biodiversity component analyses, and/or interdisciplinary studies to solve problems with more direct socio-environmental and/or economic impact. This includes studies in the fields of ecotoxicology and environmental microbiology with a focus on the characterization, monitoring, and mitigation of environmental impacts, as well as the development of more sustainable agricultural methods using components of Brazil's native biodiversity. It also includes projects aimed at developing innovative products from biodiversity sources and/or integrating biodiversity analyses into regional economic development models with a focus on environmental sustainability. |
| COD | Workload | Description |
| 196MZ-02 | 30 | Enable graduate students to understand and apply the fundamental and advanced contents inherent in molecular biology, basic genetic mechanisms (DNA, Genes, RNA and Protein) and biotechnology. |
| Professors | Home time | Lattes |
| CRISTIANO VALIM BIZARRO | 12 years and 9 months | Link |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Required |
| Cellular and Molecular Biology | Doctorate | Required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 73154-02 | 30 | This course is intended to equip students to take part in discussions on bacteriology at the molecular level, including topics in bacterial cytology, physiology, and genetics, as well as to understand the bacterial interactions with their host, which are relevant for the understanding of pathogenicity. |
| No offer for current semester |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 73151-02 | 30 | This course will deal with the molecular aspects involved in the interaction between parasite-host, by using models to study typical characteristics of parasitic life, virulence control mechanisms and strategies for diagnosis and immunization in parasitology. |
| No offer for current semester |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 73121-04 | 60 | This course is intended to enable students to understand and apply the laboratory techniques that are employed in biological research as well as to select, organize and analyze data resulting from scientific research. |
| No offer for current semester |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 73129-02 | 30 | This course is intended to provide students with a deeper understanding of cellular and molecular bases of pathologies associated with neurodegeneration, and events leading to it, by discussing the selective neuronal vulnerability. As well as that, it will address animal models and possible targets for therapeutic intervention. |
| No offer for current semester |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 1935N-02 | 30 | Processes mediated by limited proteolysis have important pathophysiological repercussions. The study of proteases and the processes in which they operate has a multidisciplinary character, involving knowledge in biochemistry, biophysics and physiology of the systems involved. The course will address fundamental concepts about proteolytic enzymes and their inhibitors, and special emphasis will be given to pathologies involving limited proteolysis, according to the following topics: i. Proteolytic enzymes: general aspects ii. Protease inhibitors: classes iii. Blood clotting and fibrinolysis iv. Complement system v. Prohormone convertases and oligopeptidases saw. Beta-convertase pathway and formation of amyloid peptides vii. Caspases and apoptosis viii. Proteasome and ubiquitination ix. Proteolysis in embryonic development |
| No offer for current semester |
| Concentration area | Type | Required |
| Biochemical and Molecular Pharmacology | Master's | Not required |
| Biochemical and Molecular Pharmacology | Doctorate | Not required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Medical Practice | Master's | Not required |
| Medical Practice | Doctorate | Not required |
| Nephrology | Master's | Not required |
| Nephrology | Doctorate | Not required |
| Neurosciences | Master's | Not required |
| Neurosciences | Doctorate | Not required |
| Surgical Practice | Master's | Not required |
| Surgical Practice | Doctorate | Not required |
| Research line | Description |
| Evaluation of mechanisms involved in inflammatory and nociceptive alterations | This line of research is concerned with the evaluation of mechanisms involved in inflammatory and nociceptive alterations |
| Drug Development | This line of research has been designed for the development of drugs against neglected tropical diseases (tuberculosis and malaria) and the development of drugs against chronic and degenerative diseases. |
| Evaluation of pharmacological targets in cancer treatment | This line of research is concerned with the evaluation of pharmacological targets in cancer treatment and inflammation. |
| Analysis and evaluation of neurochemical and pharmacological mechanisms in neurological diseases | Study of the neurochemical roots and pharmacological targets in neurological diseases. |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| Extra-renal dialysis and transplatation | This line of research is intended for the study of different modalities of renal replacement therapies, with emphasis on organ transplantation, especially when it comes to immunology of transplants. |
| Clinical nephrology and arterial hypertension | This line of research will address topics related to several aspects of clinical nephrology, renal function, arterial hypertension, renal and metabolic diseases. |
| Molecular Biology, immunology and stem cell | This line of research is concerned with the study of molecular alterations in tumors, mainly those affecting the digestive and respiratory systems, through PCR techniques in real time, immunohistochemistry, flow cytometry and cell cultivation. It will also look at Cell Therapy and Tissue Engineering. |
| Cardiology/Risk Factors and genetics factors in cardiovascular diseases | This line of research is concerned with assessing risk factors for cardiovascular surgeries using markers; traditional risk factors (dyslipidemias, arterial hypertension, diabetes, smoke addiction) and potential emerging ones (apolipoprotein B,small and dense LDL cholesterol) in coronary heart diseases. |
| Cardiology/Cellular therapy | This line of research is intended to assess the efficiency and safety of autologous implants of bone marrow stem cells in patients suffering from dilated cardiomyopathy and in patients suffering from acute myocardial infarction. |
| Cellular metabolism and membrane transport in renal and metabolic diseases (or disease states) | This line of research is designed for the study of physiopathogenic mechanisms of several renal and metabolic diseases. |
| Training and Faculty Development in Health | |
| Study abdomen adult and elderly healthy and sick with new technologies in Diagnostic Imaging | First of all, this line of research is intended to introduce students to different abdominal organs in advanced imaging modalities, such as magnetic resonance and positron emission tomography. It is intended to study the normal anatomy of these organs and tissues and their anatomic variations, thus allowing for a comparison between healthy and unhealthy individuals. With this, we intent to provide deeper insights into the abdomen's normal anatomy and its anatomic variation through new imaging technologies. Additionally, this line of research will determine the diagnostic imaging accuracy of gastrointestinal tract and urinary system diseases. We are intent on reaching an earlier and more precise diagnosis of the diseases of adult and elderly patients, thus increasing their survival. It has been designed to produce researchers and professors who want to work within this line of research responsible for studying the most common diseases in our population. |
| Clinical Epidemiology | This area of concentration is intended to develop research in clinical epidemiology focusing on its methodological and clinical aspects. This line of research intends to encourage the development of research projects that contribute to the progress in identification, intervention and promotion of determinants of the health-disease process in human population. |
| Functional and Molecular Image of the Body | Functional imaging is the state-of-the-art in diagnostic imaging. Magnetic Resonance made a giant leap in that direction through the employment of ultra-rapid acquisition techniques, which have enabled the measurement of variations in oxygen consumption levels arising from the BOLD effect and an estimation of the cellularity of tissues through the diffusion technique. PET has enabled Nuclear Medicine to measure the level of consumption of glucose in the tissue, by making use of ionizing radiation. It is largely employed in the investigation of tumors and metastasis, which have naturally increased the consumption of glucose due to a larger metabolic level. More recently, the Dynamic PET has enabled the assessment of the consumption of glucose over time and the measurement of the most active regions more precisely. |
| Epidemiology and Environmental Health | This course is intended to encourage the development of research into the area of epidemiology and environmental health with an eye to the methodological and clinical aspects. This line of research seeks to encourage the development of research projects that contribute to the advancement of the identification, intervention and promotion of the determinants of the health-disease process in human population. |
| Technological Innovations in the Health Area | Curently, we are seeing worldwide the fast development of technologies, proceedings and medicines focus at the most effective treatment of diseases and the restoration of health. This accelerated step with which medical knowledge progresses makes it necessary to create a new mentality in medical training, stimulating curiosity, the active search for knowledge and constant updating. The number and complexity of the scientific processes that lead to this evolution are also worthy of attention, both due to the need for training to understand them, as well as the work opportunity they represent for doctors in general. |
| Neurology/ stem cells | This line of research is concerned with the assessment of the possibility of regeneration of central and peripheral neurological injuries resulting from neurodegenerative diseases, with somatic stem cells, as well as with the study of the structural and functional mechanisms of regeneration from injuries. |
| Behavioral neurology and neuropsychiatry | This line of research will look at the neurobiology of psychiatric diseases and behavioral alterations in major neurological diseases. |
| Cognitive brain imaging | This line of research will look at the development of new techniques for the analysis of neuroimaging and studies of neural bases of superior cognitive processes (for instance, language comprehension and acquisition, executive functions, spatial reasoning). |
| Neurotoxic activity of ureases and derived peptides | This line of research will address the neurotoxic and pro-inflammatory activities of ureases of different organisms. It will also address the methodologies of study of neurotoxicity relying on the use of insects-models. As well as this, it will look at ureases as virulence factors for pathogenic microorganisms, especially bacteria Helicobacter pylori and Proteus mirabilis and Cryptococcu yeasts. |
| Neuroinflammation/Multiple Sclerosis/ neuromyelitis optica | The inflammation resulting from neurological diseases may be primarily involved with the physiopathology of immunomediated diseases of the nervous system, such as multiple sclerosis, neuromyelitis optica, ADEM - acute demyelinating encephalomyelitis, Guillain-Barré syndrome, autoimmune encephalitis and some neurological complications resulting directly or indirectly from viral or bacterial infections (e.g. meningoencephalitis). In other diseases, the inflammation plays a major role, but less clear than it is in strokes and in degenerative diseases of the central nervous system. The deregulation in the immune system, be it either temporary or permanent, may lead to injuries in the brain, bone marrow and peripheral nerves that cause permanent neuronal damage with the risk of aftereffects and permanent incapacity. By relying on advanced methods in molecular biology associated with clinical and imaging assessment (magnetic resonance, nuclear medicine), we have conducted research that is intended to understand the intrinsic and extrinsic mechanisms that lead to an increase of pro-inflammatory substances such as cytokines, chemokines, the production of autoantibodies, complement system activation, proliferation / maturation of autoreactive lymphocytes T and B, microglial activation and the alteration of the blood-brain barrier. Besides, we have conducted research for the identification of specific biomarkers for each disease which may assist in the establishment of better diagnosis/prognosis and in experimental animal models for the study of physiopathology and innovative therapeutic interventions. |
| Epilepsy | This line of research will cover clinical and electroencephalographic, pharmacological, neuroimaging and surgical studies in the realm of epilepsy. The direct involvement of São Lucas Hospital with the diagnosis, clinical treatment and epilepsy surgery opens interesting perspectives of investigation, seeking diagnostic refinement, new treatment options and the correlations of epileptic syndromes with structural alterations of the brain. |
| The central nervous system (CNS) formation stages can be considered a great concert with the regency of different signaling molecules that trigger a cascade of dependent and complementary processes until the formation of all CNS structures as well as their different functionalities. The human brain is a puzzle of more than 100 billion pieces that must be accurately directed to its unique and specific location. The studies of Molecurar Bases of Embryonic Neurogenesis presents a comprehensive view of understanding the CNS, from its embryonic formation to neurogenesis in the adult brain, guiding clinical and pathological situations related to cerebral malformations and new therapeutic alternatives for CNS recovery. The use of molecular techniques as next-generation sequencing (NGS), super arrays, relative expression, genotyping, etc., are used to describe signaling pathways, genesis of pathologies, and application of precision medicine for the treatment of various diseases. The cell reprogramming at the embryonic level through the generation of induced pluripotent stem cells (iPSC) helps to understand embryonic neurogenesis and screening of new drugs for the treatment of alterations during the formation of the central nervous system and its associated pathologies | |
| Artificial Intelligence in Healthcare | Fluency in oral reading is a crucial skill for children and adolescents, involving the ability to read a text with accuracy, appropriate expression, and at a determined pace. Artificial intelligence has enabled considerable advances in activities that previously required time and attention from specialized professionals, also offering the advantage of impartial evaluation. Moreover, a significant portion of students in Brazil presents literacy difficulties associated with reading skills and lacks adequate assistance and diagnosis for conditions such as dyslexia. This research line aims to encompass research projects at the intersection of health, education, and artificial intelligence. The studies seek to investigate tools for assessing oral reading through innovative technologies, which can be used by health professionals in collaboration with educators. These tools aim to assist in identifying the level of reading development, factors influencing these skills, association with academic performance, early screening of signs of difficulties and disorders affecting reading fluency, differential diagnoses, as well as the appropriate medical/educational conduct. |
| Obesity and Metabolic Syndrome | This line is concerned with research in the area of obesity and metabolic syndrome with consequences in co-morbidities involved or related to the aforementioned pathologies. |
| Epidemiological, Clinicopathological, Radiological and Molecular aspects of malignant neoplasms. | This area of concentration is intended to describe patients who suffer from malignant neoplasms in their different clinical stages, as well as to assess their clinical outcome by looking at the clinical, histopathological, radiological and molecular variables. Studies in this area may be accountable for addressing some issues that are still controversial among the scientific community. |
| Videolaparoscopic Surgery | This area of concentration is intended to assess the advantages of the procedures conducted using less invasive techniques. |
| COD | Workload | Description |
| 19505-02 | 30 | This course aims to increase knowledge in the field of pharmacology and toxicology, with particular emphasis on biochemical and molecular aspects that influence the action of drugs. It will be addressed aspects of general pharmacology, such as pharmacokinetics and pharmacodynamics. These aspects will be studied both at the level of basic and applied science, seeking to integrate these two areas of pharmacological knowledge. It will be addressed the stages of intoxication, exposure, toxicokinetic, toxicodynamic and clinical, and the dose / response curve. |
| Professors | Home time | Lattes |
| FERNANDA BUENO MORRONE | 24 years and 9 months | Link |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 1932A-01 | 15 | Neuropharmacology is the study of the effect of drugs on the brain. The seminars explore the concepts and current research in cognitive neuroscience, including perception, brain structure and organization, cognition, memory and the functional basis of certain human neurological and psychiatric illnesses. (e.g. schizophrenia, depression and Narcolepsy). The purpose of this course is to provide students with an opportunity to acquire the theoretical and applied knowledge of neuropharmacology that will enable them to proceed into developing a career in neuropharmacology either in an academic institution, a research institute or in the industrial/business sector. |
| No offer for current semester |
| Concentration area | Type | Required |
| Biochemical and Molecular Pharmacology | Master's | Not required |
| Biochemical and Molecular Pharmacology | Doctorate | Not required |
| Biomedical Gerontology | Master's | Not required |
| Biomedical Gerontology | Doctorate | Not required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Medical Practice | Master's | Not required |
| Medical Practice | Doctorate | Not required |
| Nephrology | Master's | Not required |
| Nephrology | Doctorate | Not required |
| Neurosciences | Master's | Not required |
| Neurosciences | Doctorate | Not required |
| Pediatrics | Master's | Not required |
| Pediatrics | Doctorate | Not required |
| Pharmaceutical Biotechnology | Professional Master's | Not required |
| Surgical Practice | Master's | Not required |
| Surgical Practice | Doctorate | Not required |
| Research line | Description |
| Evaluation of mechanisms involved in inflammatory and nociceptive alterations | This line of research is concerned with the evaluation of mechanisms involved in inflammatory and nociceptive alterations |
| Drug Development | This line of research has been designed for the development of drugs against neglected tropical diseases (tuberculosis and malaria) and the development of drugs against chronic and degenerative diseases. |
| Evaluation of pharmacological targets in cancer treatment | This line of research is concerned with the evaluation of pharmacological targets in cancer treatment and inflammation. |
| Analysis and evaluation of neurochemical and pharmacological mechanisms in neurological diseases | Study of the neurochemical roots and pharmacological targets in neurological diseases. |
| Biological Aspects of Aging | This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo). |
| Clinical and Emotional Aspects of Aging | This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition. |
| Social-cultural, Demographic and Bioethical Aspects of Aging | This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging. |
| Aging and Public Health | This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life. |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| Extra-renal dialysis and transplatation | This line of research is intended for the study of different modalities of renal replacement therapies, with emphasis on organ transplantation, especially when it comes to immunology of transplants. |
| Clinical nephrology and arterial hypertension | This line of research will address topics related to several aspects of clinical nephrology, renal function, arterial hypertension, renal and metabolic diseases. |
| Molecular Biology, immunology and stem cell | This line of research is concerned with the study of molecular alterations in tumors, mainly those affecting the digestive and respiratory systems, through PCR techniques in real time, immunohistochemistry, flow cytometry and cell cultivation. It will also look at Cell Therapy and Tissue Engineering. |
| Cardiology/Risk Factors and genetics factors in cardiovascular diseases | This line of research is concerned with assessing risk factors for cardiovascular surgeries using markers; traditional risk factors (dyslipidemias, arterial hypertension, diabetes, smoke addiction) and potential emerging ones (apolipoprotein B,small and dense LDL cholesterol) in coronary heart diseases. |
| Cardiology/Cellular therapy | This line of research is intended to assess the efficiency and safety of autologous implants of bone marrow stem cells in patients suffering from dilated cardiomyopathy and in patients suffering from acute myocardial infarction. |
| Cellular metabolism and membrane transport in renal and metabolic diseases (or disease states) | This line of research is designed for the study of physiopathogenic mechanisms of several renal and metabolic diseases. |
| Training and Faculty Development in Health | |
| Study abdomen adult and elderly healthy and sick with new technologies in Diagnostic Imaging | First of all, this line of research is intended to introduce students to different abdominal organs in advanced imaging modalities, such as magnetic resonance and positron emission tomography. It is intended to study the normal anatomy of these organs and tissues and their anatomic variations, thus allowing for a comparison between healthy and unhealthy individuals. With this, we intent to provide deeper insights into the abdomen's normal anatomy and its anatomic variation through new imaging technologies. Additionally, this line of research will determine the diagnostic imaging accuracy of gastrointestinal tract and urinary system diseases. We are intent on reaching an earlier and more precise diagnosis of the diseases of adult and elderly patients, thus increasing their survival. It has been designed to produce researchers and professors who want to work within this line of research responsible for studying the most common diseases in our population. |
| Clinical Epidemiology | This area of concentration is intended to develop research in clinical epidemiology focusing on its methodological and clinical aspects. This line of research intends to encourage the development of research projects that contribute to the progress in identification, intervention and promotion of determinants of the health-disease process in human population. |
| Functional and Molecular Image of the Body | Functional imaging is the state-of-the-art in diagnostic imaging. Magnetic Resonance made a giant leap in that direction through the employment of ultra-rapid acquisition techniques, which have enabled the measurement of variations in oxygen consumption levels arising from the BOLD effect and an estimation of the cellularity of tissues through the diffusion technique. PET has enabled Nuclear Medicine to measure the level of consumption of glucose in the tissue, by making use of ionizing radiation. It is largely employed in the investigation of tumors and metastasis, which have naturally increased the consumption of glucose due to a larger metabolic level. More recently, the Dynamic PET has enabled the assessment of the consumption of glucose over time and the measurement of the most active regions more precisely. |
| Epidemiology and Environmental Health | This course is intended to encourage the development of research into the area of epidemiology and environmental health with an eye to the methodological and clinical aspects. This line of research seeks to encourage the development of research projects that contribute to the advancement of the identification, intervention and promotion of the determinants of the health-disease process in human population. |
| Technological Innovations in the Health Area | Curently, we are seeing worldwide the fast development of technologies, proceedings and medicines focus at the most effective treatment of diseases and the restoration of health. This accelerated step with which medical knowledge progresses makes it necessary to create a new mentality in medical training, stimulating curiosity, the active search for knowledge and constant updating. The number and complexity of the scientific processes that lead to this evolution are also worthy of attention, both due to the need for training to understand them, as well as the work opportunity they represent for doctors in general. |
| Neurology/ stem cells | This line of research is concerned with the assessment of the possibility of regeneration of central and peripheral neurological injuries resulting from neurodegenerative diseases, with somatic stem cells, as well as with the study of the structural and functional mechanisms of regeneration from injuries. |
| Behavioral neurology and neuropsychiatry | This line of research will look at the neurobiology of psychiatric diseases and behavioral alterations in major neurological diseases. |
| Cognitive brain imaging | This line of research will look at the development of new techniques for the analysis of neuroimaging and studies of neural bases of superior cognitive processes (for instance, language comprehension and acquisition, executive functions, spatial reasoning). |
| Neurotoxic activity of ureases and derived peptides | This line of research will address the neurotoxic and pro-inflammatory activities of ureases of different organisms. It will also address the methodologies of study of neurotoxicity relying on the use of insects-models. As well as this, it will look at ureases as virulence factors for pathogenic microorganisms, especially bacteria Helicobacter pylori and Proteus mirabilis and Cryptococcu yeasts. |
| Neuroinflammation/Multiple Sclerosis/ neuromyelitis optica | The inflammation resulting from neurological diseases may be primarily involved with the physiopathology of immunomediated diseases of the nervous system, such as multiple sclerosis, neuromyelitis optica, ADEM - acute demyelinating encephalomyelitis, Guillain-Barré syndrome, autoimmune encephalitis and some neurological complications resulting directly or indirectly from viral or bacterial infections (e.g. meningoencephalitis). In other diseases, the inflammation plays a major role, but less clear than it is in strokes and in degenerative diseases of the central nervous system. The deregulation in the immune system, be it either temporary or permanent, may lead to injuries in the brain, bone marrow and peripheral nerves that cause permanent neuronal damage with the risk of aftereffects and permanent incapacity. By relying on advanced methods in molecular biology associated with clinical and imaging assessment (magnetic resonance, nuclear medicine), we have conducted research that is intended to understand the intrinsic and extrinsic mechanisms that lead to an increase of pro-inflammatory substances such as cytokines, chemokines, the production of autoantibodies, complement system activation, proliferation / maturation of autoreactive lymphocytes T and B, microglial activation and the alteration of the blood-brain barrier. Besides, we have conducted research for the identification of specific biomarkers for each disease which may assist in the establishment of better diagnosis/prognosis and in experimental animal models for the study of physiopathology and innovative therapeutic interventions. |
| Epilepsy | This line of research will cover clinical and electroencephalographic, pharmacological, neuroimaging and surgical studies in the realm of epilepsy. The direct involvement of São Lucas Hospital with the diagnosis, clinical treatment and epilepsy surgery opens interesting perspectives of investigation, seeking diagnostic refinement, new treatment options and the correlations of epileptic syndromes with structural alterations of the brain. |
| The central nervous system (CNS) formation stages can be considered a great concert with the regency of different signaling molecules that trigger a cascade of dependent and complementary processes until the formation of all CNS structures as well as their different functionalities. The human brain is a puzzle of more than 100 billion pieces that must be accurately directed to its unique and specific location. The studies of Molecurar Bases of Embryonic Neurogenesis presents a comprehensive view of understanding the CNS, from its embryonic formation to neurogenesis in the adult brain, guiding clinical and pathological situations related to cerebral malformations and new therapeutic alternatives for CNS recovery. The use of molecular techniques as next-generation sequencing (NGS), super arrays, relative expression, genotyping, etc., are used to describe signaling pathways, genesis of pathologies, and application of precision medicine for the treatment of various diseases. The cell reprogramming at the embryonic level through the generation of induced pluripotent stem cells (iPSC) helps to understand embryonic neurogenesis and screening of new drugs for the treatment of alterations during the formation of the central nervous system and its associated pathologies | |
| Artificial Intelligence in Healthcare | Fluency in oral reading is a crucial skill for children and adolescents, involving the ability to read a text with accuracy, appropriate expression, and at a determined pace. Artificial intelligence has enabled considerable advances in activities that previously required time and attention from specialized professionals, also offering the advantage of impartial evaluation. Moreover, a significant portion of students in Brazil presents literacy difficulties associated with reading skills and lacks adequate assistance and diagnosis for conditions such as dyslexia. This research line aims to encompass research projects at the intersection of health, education, and artificial intelligence. The studies seek to investigate tools for assessing oral reading through innovative technologies, which can be used by health professionals in collaboration with educators. These tools aim to assist in identifying the level of reading development, factors influencing these skills, association with academic performance, early screening of signs of difficulties and disorders affecting reading fluency, differential diagnoses, as well as the appropriate medical/educational conduct. |
| Obesity and Metabolic Syndrome | This line is concerned with research in the area of obesity and metabolic syndrome with consequences in co-morbidities involved or related to the aforementioned pathologies. |
| Epidemiological, Clinicopathological, Radiological and Molecular aspects of malignant neoplasms. | This area of concentration is intended to describe patients who suffer from malignant neoplasms in their different clinical stages, as well as to assess their clinical outcome by looking at the clinical, histopathological, radiological and molecular variables. Studies in this area may be accountable for addressing some issues that are still controversial among the scientific community. |
| Videolaparoscopic Surgery | This area of concentration is intended to assess the advantages of the procedures conducted using less invasive techniques. |
| COD | Workload | Description |
| 63444-02 | 30 | The study of animal poisons (reptiles, anthropoides and mollusks) and natural toxins (microbial ones and plants) has a multidisciplinary nature, and will address the structural aspects of toxic molecules, their mechanisms of action and how they manifest in patients, up to the treatment of clinical cases. Another aspect of the study of these molecules is the design of new toxin-based therapeutic drugs, based on the understanding of their interactions with cell targets. In this context, this course is intended to address the main groups of proteins and toxic peptides found in animal poisons, as well as toxins produced by plants and bacteria. The molecular aspects and mechanisms of action of the main groups of protein and peptide proteins will be addressed, as well as a discussion of the clinical cases representing each type of poison/toxin. To follow are the groups of toxins to be addressed: 1. phospholipases of poisons of serpents and anthropoides: hemotoxins, neurotoxins and mycotoxins; 2. toxins interfering with G proteins: ADP-riboses (cholera and pertussis toxins) shiga toxins; 3. clostridial toxins and anthrax zync - metalloproteinase (tetanus and botulinum toxins); 4. toxins interfering in protein synthesis: RNA N-glucosidases (ricin and abrin) ADP-riboses (diphtheria toxin, pseudomonas and exotoxin A); 5. toxins affecting ion channels, serpents (A-bungatoxin, three-fingers, phospholipases) arthropodes (tityustoxin, A-latrotoxin, charabtoxin, etc.) mollusks (conotoxins). |
| No offer for current semester |
| Concentration area | Type | Required |
| Biochemical and Molecular Pharmacology | Master's | Not required |
| Biochemical and Molecular Pharmacology | Doctorate | Not required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Medical Practice | Master's | Not required |
| Medical Practice | Doctorate | Not required |
| Nephrology | Master's | Not required |
| Nephrology | Doctorate | Not required |
| Neurosciences | Master's | Not required |
| Neurosciences | Doctorate | Not required |
| Surgical Practice | Master's | Not required |
| Surgical Practice | Doctorate | Not required |
| Research line | Description |
| Evaluation of mechanisms involved in inflammatory and nociceptive alterations | This line of research is concerned with the evaluation of mechanisms involved in inflammatory and nociceptive alterations |
| Drug Development | This line of research has been designed for the development of drugs against neglected tropical diseases (tuberculosis and malaria) and the development of drugs against chronic and degenerative diseases. |
| Evaluation of pharmacological targets in cancer treatment | This line of research is concerned with the evaluation of pharmacological targets in cancer treatment and inflammation. |
| Analysis and evaluation of neurochemical and pharmacological mechanisms in neurological diseases | Study of the neurochemical roots and pharmacological targets in neurological diseases. |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| Extra-renal dialysis and transplatation | This line of research is intended for the study of different modalities of renal replacement therapies, with emphasis on organ transplantation, especially when it comes to immunology of transplants. |
| Clinical nephrology and arterial hypertension | This line of research will address topics related to several aspects of clinical nephrology, renal function, arterial hypertension, renal and metabolic diseases. |
| Molecular Biology, immunology and stem cell | This line of research is concerned with the study of molecular alterations in tumors, mainly those affecting the digestive and respiratory systems, through PCR techniques in real time, immunohistochemistry, flow cytometry and cell cultivation. It will also look at Cell Therapy and Tissue Engineering. |
| Cardiology/Risk Factors and genetics factors in cardiovascular diseases | This line of research is concerned with assessing risk factors for cardiovascular surgeries using markers; traditional risk factors (dyslipidemias, arterial hypertension, diabetes, smoke addiction) and potential emerging ones (apolipoprotein B,small and dense LDL cholesterol) in coronary heart diseases. |
| Cardiology/Cellular therapy | This line of research is intended to assess the efficiency and safety of autologous implants of bone marrow stem cells in patients suffering from dilated cardiomyopathy and in patients suffering from acute myocardial infarction. |
| Cellular metabolism and membrane transport in renal and metabolic diseases (or disease states) | This line of research is designed for the study of physiopathogenic mechanisms of several renal and metabolic diseases. |
| Training and Faculty Development in Health | |
| Study abdomen adult and elderly healthy and sick with new technologies in Diagnostic Imaging | First of all, this line of research is intended to introduce students to different abdominal organs in advanced imaging modalities, such as magnetic resonance and positron emission tomography. It is intended to study the normal anatomy of these organs and tissues and their anatomic variations, thus allowing for a comparison between healthy and unhealthy individuals. With this, we intent to provide deeper insights into the abdomen's normal anatomy and its anatomic variation through new imaging technologies. Additionally, this line of research will determine the diagnostic imaging accuracy of gastrointestinal tract and urinary system diseases. We are intent on reaching an earlier and more precise diagnosis of the diseases of adult and elderly patients, thus increasing their survival. It has been designed to produce researchers and professors who want to work within this line of research responsible for studying the most common diseases in our population. |
| Clinical Epidemiology | This area of concentration is intended to develop research in clinical epidemiology focusing on its methodological and clinical aspects. This line of research intends to encourage the development of research projects that contribute to the progress in identification, intervention and promotion of determinants of the health-disease process in human population. |
| Functional and Molecular Image of the Body | Functional imaging is the state-of-the-art in diagnostic imaging. Magnetic Resonance made a giant leap in that direction through the employment of ultra-rapid acquisition techniques, which have enabled the measurement of variations in oxygen consumption levels arising from the BOLD effect and an estimation of the cellularity of tissues through the diffusion technique. PET has enabled Nuclear Medicine to measure the level of consumption of glucose in the tissue, by making use of ionizing radiation. It is largely employed in the investigation of tumors and metastasis, which have naturally increased the consumption of glucose due to a larger metabolic level. More recently, the Dynamic PET has enabled the assessment of the consumption of glucose over time and the measurement of the most active regions more precisely. |
| Epidemiology and Environmental Health | This course is intended to encourage the development of research into the area of epidemiology and environmental health with an eye to the methodological and clinical aspects. This line of research seeks to encourage the development of research projects that contribute to the advancement of the identification, intervention and promotion of the determinants of the health-disease process in human population. |
| Technological Innovations in the Health Area | Curently, we are seeing worldwide the fast development of technologies, proceedings and medicines focus at the most effective treatment of diseases and the restoration of health. This accelerated step with which medical knowledge progresses makes it necessary to create a new mentality in medical training, stimulating curiosity, the active search for knowledge and constant updating. The number and complexity of the scientific processes that lead to this evolution are also worthy of attention, both due to the need for training to understand them, as well as the work opportunity they represent for doctors in general. |
| Neurology/ stem cells | This line of research is concerned with the assessment of the possibility of regeneration of central and peripheral neurological injuries resulting from neurodegenerative diseases, with somatic stem cells, as well as with the study of the structural and functional mechanisms of regeneration from injuries. |
| Behavioral neurology and neuropsychiatry | This line of research will look at the neurobiology of psychiatric diseases and behavioral alterations in major neurological diseases. |
| Cognitive brain imaging | This line of research will look at the development of new techniques for the analysis of neuroimaging and studies of neural bases of superior cognitive processes (for instance, language comprehension and acquisition, executive functions, spatial reasoning). |
| Neurotoxic activity of ureases and derived peptides | This line of research will address the neurotoxic and pro-inflammatory activities of ureases of different organisms. It will also address the methodologies of study of neurotoxicity relying on the use of insects-models. As well as this, it will look at ureases as virulence factors for pathogenic microorganisms, especially bacteria Helicobacter pylori and Proteus mirabilis and Cryptococcu yeasts. |
| Neuroinflammation/Multiple Sclerosis/ neuromyelitis optica | The inflammation resulting from neurological diseases may be primarily involved with the physiopathology of immunomediated diseases of the nervous system, such as multiple sclerosis, neuromyelitis optica, ADEM - acute demyelinating encephalomyelitis, Guillain-Barré syndrome, autoimmune encephalitis and some neurological complications resulting directly or indirectly from viral or bacterial infections (e.g. meningoencephalitis). In other diseases, the inflammation plays a major role, but less clear than it is in strokes and in degenerative diseases of the central nervous system. The deregulation in the immune system, be it either temporary or permanent, may lead to injuries in the brain, bone marrow and peripheral nerves that cause permanent neuronal damage with the risk of aftereffects and permanent incapacity. By relying on advanced methods in molecular biology associated with clinical and imaging assessment (magnetic resonance, nuclear medicine), we have conducted research that is intended to understand the intrinsic and extrinsic mechanisms that lead to an increase of pro-inflammatory substances such as cytokines, chemokines, the production of autoantibodies, complement system activation, proliferation / maturation of autoreactive lymphocytes T and B, microglial activation and the alteration of the blood-brain barrier. Besides, we have conducted research for the identification of specific biomarkers for each disease which may assist in the establishment of better diagnosis/prognosis and in experimental animal models for the study of physiopathology and innovative therapeutic interventions. |
| Epilepsy | This line of research will cover clinical and electroencephalographic, pharmacological, neuroimaging and surgical studies in the realm of epilepsy. The direct involvement of São Lucas Hospital with the diagnosis, clinical treatment and epilepsy surgery opens interesting perspectives of investigation, seeking diagnostic refinement, new treatment options and the correlations of epileptic syndromes with structural alterations of the brain. |
| The central nervous system (CNS) formation stages can be considered a great concert with the regency of different signaling molecules that trigger a cascade of dependent and complementary processes until the formation of all CNS structures as well as their different functionalities. The human brain is a puzzle of more than 100 billion pieces that must be accurately directed to its unique and specific location. The studies of Molecurar Bases of Embryonic Neurogenesis presents a comprehensive view of understanding the CNS, from its embryonic formation to neurogenesis in the adult brain, guiding clinical and pathological situations related to cerebral malformations and new therapeutic alternatives for CNS recovery. The use of molecular techniques as next-generation sequencing (NGS), super arrays, relative expression, genotyping, etc., are used to describe signaling pathways, genesis of pathologies, and application of precision medicine for the treatment of various diseases. The cell reprogramming at the embryonic level through the generation of induced pluripotent stem cells (iPSC) helps to understand embryonic neurogenesis and screening of new drugs for the treatment of alterations during the formation of the central nervous system and its associated pathologies | |
| Artificial Intelligence in Healthcare | Fluency in oral reading is a crucial skill for children and adolescents, involving the ability to read a text with accuracy, appropriate expression, and at a determined pace. Artificial intelligence has enabled considerable advances in activities that previously required time and attention from specialized professionals, also offering the advantage of impartial evaluation. Moreover, a significant portion of students in Brazil presents literacy difficulties associated with reading skills and lacks adequate assistance and diagnosis for conditions such as dyslexia. This research line aims to encompass research projects at the intersection of health, education, and artificial intelligence. The studies seek to investigate tools for assessing oral reading through innovative technologies, which can be used by health professionals in collaboration with educators. These tools aim to assist in identifying the level of reading development, factors influencing these skills, association with academic performance, early screening of signs of difficulties and disorders affecting reading fluency, differential diagnoses, as well as the appropriate medical/educational conduct. |
| Obesity and Metabolic Syndrome | This line is concerned with research in the area of obesity and metabolic syndrome with consequences in co-morbidities involved or related to the aforementioned pathologies. |
| Epidemiological, Clinicopathological, Radiological and Molecular aspects of malignant neoplasms. | This area of concentration is intended to describe patients who suffer from malignant neoplasms in their different clinical stages, as well as to assess their clinical outcome by looking at the clinical, histopathological, radiological and molecular variables. Studies in this area may be accountable for addressing some issues that are still controversial among the scientific community. |
| Videolaparoscopic Surgery | This area of concentration is intended to assess the advantages of the procedures conducted using less invasive techniques. |
| COD | Workload | Description |
| 63348-04 | 60 | Knowing how to use computer tools is fundamental for conducting research in health. This course is intended to explore, in a practical way, important software for medical research. The focus will be on online resources, spreadsheets, graphic programs, statistical programs, word processors, and bibliographic reference management. |
| No offer for current semester |
| Concentration area | Type | Required |
| Biochemical and Molecular Pharmacology | Master's | Not required |
| Biochemical and Molecular Pharmacology | Doctorate | Not required |
| Biomedical Gerontology | Master's | Not required |
| Biomedical Gerontology | Doctorate | Not required |
| CTBMF | Master's | Not required |
| CTBMF | Doctorate | Not required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Clinical Psychology | Master's | Not required |
| Clinical Psychology | Doctorate | Not required |
| Clinical Stomatology | Master's | Not required |
| Clinical Stomatology | Doctorate | Not required |
| Dental Materials | Master's | Not required |
| Dental Materials | Doctorate | Not required |
| Dental Prosthetics | Master's | Not required |
| Dental Prosthetics | Doctorate | Not required |
| Endodontics | Master's | Not required |
| Endodontics | Doctorate | Not required |
| Human Cognition | Master's | Not required |
| Human Cognition | Doctorate | Not required |
| Medical Practice | Master's | Not required |
| Medical Practice | Doctorate | Not required |
| Nephrology | Master's | Not required |
| Nephrology | Doctorate | Not required |
| Neurosciences | Master's | Not required |
| Neurosciences | Doctorate | Not required |
| Orthodontics and Facial Orthopedics | Master's | Not required |
| Orthodontics and Facial Orthopedics | Doctorate | Not required |
| Pediatrics | Master's | Not required |
| Pediatrics | Inter-institutional doctorate degree | Not required |
| Pediatrics | Doctorate | Not required |
| Psychology | Doctorate | Not required |
| Restorative Dentistry | Master's | Not required |
| Restorative Dentistry | Doctorate | Not required |
| Social Psychology | Master's | Not required |
| Social Psychology | Doctorate | Not required |
| Surgical Practice | Master's | Not required |
| Surgical Practice | Doctorate | Not required |
| Research line | Description |
| Evaluation of mechanisms involved in inflammatory and nociceptive alterations | This line of research is concerned with the evaluation of mechanisms involved in inflammatory and nociceptive alterations |
| Drug Development | This line of research has been designed for the development of drugs against neglected tropical diseases (tuberculosis and malaria) and the development of drugs against chronic and degenerative diseases. |
| Evaluation of pharmacological targets in cancer treatment | This line of research is concerned with the evaluation of pharmacological targets in cancer treatment and inflammation. |
| Analysis and evaluation of neurochemical and pharmacological mechanisms in neurological diseases | Study of the neurochemical roots and pharmacological targets in neurological diseases. |
| Biological Aspects of Aging | This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo). |
| Clinical and Emotional Aspects of Aging | This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition. |
| Social-cultural, Demographic and Bioethical Aspects of Aging | This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging. |
| Aging and Public Health | This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life. |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| Extra-renal dialysis and transplatation | This line of research is intended for the study of different modalities of renal replacement therapies, with emphasis on organ transplantation, especially when it comes to immunology of transplants. |
| Clinical nephrology and arterial hypertension | This line of research will address topics related to several aspects of clinical nephrology, renal function, arterial hypertension, renal and metabolic diseases. |
| Molecular Biology, immunology and stem cell | This line of research is concerned with the study of molecular alterations in tumors, mainly those affecting the digestive and respiratory systems, through PCR techniques in real time, immunohistochemistry, flow cytometry and cell cultivation. It will also look at Cell Therapy and Tissue Engineering. |
| Cardiology/Risk Factors and genetics factors in cardiovascular diseases | This line of research is concerned with assessing risk factors for cardiovascular surgeries using markers; traditional risk factors (dyslipidemias, arterial hypertension, diabetes, smoke addiction) and potential emerging ones (apolipoprotein B,small and dense LDL cholesterol) in coronary heart diseases. |
| Cardiology/Cellular therapy | This line of research is intended to assess the efficiency and safety of autologous implants of bone marrow stem cells in patients suffering from dilated cardiomyopathy and in patients suffering from acute myocardial infarction. |
| Cellular metabolism and membrane transport in renal and metabolic diseases (or disease states) | This line of research is designed for the study of physiopathogenic mechanisms of several renal and metabolic diseases. |
| Training and Faculty Development in Health | |
| Study abdomen adult and elderly healthy and sick with new technologies in Diagnostic Imaging | First of all, this line of research is intended to introduce students to different abdominal organs in advanced imaging modalities, such as magnetic resonance and positron emission tomography. It is intended to study the normal anatomy of these organs and tissues and their anatomic variations, thus allowing for a comparison between healthy and unhealthy individuals. With this, we intent to provide deeper insights into the abdomen's normal anatomy and its anatomic variation through new imaging technologies. Additionally, this line of research will determine the diagnostic imaging accuracy of gastrointestinal tract and urinary system diseases. We are intent on reaching an earlier and more precise diagnosis of the diseases of adult and elderly patients, thus increasing their survival. It has been designed to produce researchers and professors who want to work within this line of research responsible for studying the most common diseases in our population. |
| Clinical Epidemiology | This area of concentration is intended to develop research in clinical epidemiology focusing on its methodological and clinical aspects. This line of research intends to encourage the development of research projects that contribute to the progress in identification, intervention and promotion of determinants of the health-disease process in human population. |
| Functional and Molecular Image of the Body | Functional imaging is the state-of-the-art in diagnostic imaging. Magnetic Resonance made a giant leap in that direction through the employment of ultra-rapid acquisition techniques, which have enabled the measurement of variations in oxygen consumption levels arising from the BOLD effect and an estimation of the cellularity of tissues through the diffusion technique. PET has enabled Nuclear Medicine to measure the level of consumption of glucose in the tissue, by making use of ionizing radiation. It is largely employed in the investigation of tumors and metastasis, which have naturally increased the consumption of glucose due to a larger metabolic level. More recently, the Dynamic PET has enabled the assessment of the consumption of glucose over time and the measurement of the most active regions more precisely. |
| Epidemiology and Environmental Health | This course is intended to encourage the development of research into the area of epidemiology and environmental health with an eye to the methodological and clinical aspects. This line of research seeks to encourage the development of research projects that contribute to the advancement of the identification, intervention and promotion of the determinants of the health-disease process in human population. |
| Technological Innovations in the Health Area | Curently, we are seeing worldwide the fast development of technologies, proceedings and medicines focus at the most effective treatment of diseases and the restoration of health. This accelerated step with which medical knowledge progresses makes it necessary to create a new mentality in medical training, stimulating curiosity, the active search for knowledge and constant updating. The number and complexity of the scientific processes that lead to this evolution are also worthy of attention, both due to the need for training to understand them, as well as the work opportunity they represent for doctors in general. |
| Neurology/ stem cells | This line of research is concerned with the assessment of the possibility of regeneration of central and peripheral neurological injuries resulting from neurodegenerative diseases, with somatic stem cells, as well as with the study of the structural and functional mechanisms of regeneration from injuries. |
| Behavioral neurology and neuropsychiatry | This line of research will look at the neurobiology of psychiatric diseases and behavioral alterations in major neurological diseases. |
| Cognitive brain imaging | This line of research will look at the development of new techniques for the analysis of neuroimaging and studies of neural bases of superior cognitive processes (for instance, language comprehension and acquisition, executive functions, spatial reasoning). |
| Neurotoxic activity of ureases and derived peptides | This line of research will address the neurotoxic and pro-inflammatory activities of ureases of different organisms. It will also address the methodologies of study of neurotoxicity relying on the use of insects-models. As well as this, it will look at ureases as virulence factors for pathogenic microorganisms, especially bacteria Helicobacter pylori and Proteus mirabilis and Cryptococcu yeasts. |
| Neuroinflammation/Multiple Sclerosis/ neuromyelitis optica | The inflammation resulting from neurological diseases may be primarily involved with the physiopathology of immunomediated diseases of the nervous system, such as multiple sclerosis, neuromyelitis optica, ADEM - acute demyelinating encephalomyelitis, Guillain-Barré syndrome, autoimmune encephalitis and some neurological complications resulting directly or indirectly from viral or bacterial infections (e.g. meningoencephalitis). In other diseases, the inflammation plays a major role, but less clear than it is in strokes and in degenerative diseases of the central nervous system. The deregulation in the immune system, be it either temporary or permanent, may lead to injuries in the brain, bone marrow and peripheral nerves that cause permanent neuronal damage with the risk of aftereffects and permanent incapacity. By relying on advanced methods in molecular biology associated with clinical and imaging assessment (magnetic resonance, nuclear medicine), we have conducted research that is intended to understand the intrinsic and extrinsic mechanisms that lead to an increase of pro-inflammatory substances such as cytokines, chemokines, the production of autoantibodies, complement system activation, proliferation / maturation of autoreactive lymphocytes T and B, microglial activation and the alteration of the blood-brain barrier. Besides, we have conducted research for the identification of specific biomarkers for each disease which may assist in the establishment of better diagnosis/prognosis and in experimental animal models for the study of physiopathology and innovative therapeutic interventions. |
| Epilepsy | This line of research will cover clinical and electroencephalographic, pharmacological, neuroimaging and surgical studies in the realm of epilepsy. The direct involvement of São Lucas Hospital with the diagnosis, clinical treatment and epilepsy surgery opens interesting perspectives of investigation, seeking diagnostic refinement, new treatment options and the correlations of epileptic syndromes with structural alterations of the brain. |
| The central nervous system (CNS) formation stages can be considered a great concert with the regency of different signaling molecules that trigger a cascade of dependent and complementary processes until the formation of all CNS structures as well as their different functionalities. The human brain is a puzzle of more than 100 billion pieces that must be accurately directed to its unique and specific location. The studies of Molecurar Bases of Embryonic Neurogenesis presents a comprehensive view of understanding the CNS, from its embryonic formation to neurogenesis in the adult brain, guiding clinical and pathological situations related to cerebral malformations and new therapeutic alternatives for CNS recovery. The use of molecular techniques as next-generation sequencing (NGS), super arrays, relative expression, genotyping, etc., are used to describe signaling pathways, genesis of pathologies, and application of precision medicine for the treatment of various diseases. The cell reprogramming at the embryonic level through the generation of induced pluripotent stem cells (iPSC) helps to understand embryonic neurogenesis and screening of new drugs for the treatment of alterations during the formation of the central nervous system and its associated pathologies | |
| Artificial Intelligence in Healthcare | Fluency in oral reading is a crucial skill for children and adolescents, involving the ability to read a text with accuracy, appropriate expression, and at a determined pace. Artificial intelligence has enabled considerable advances in activities that previously required time and attention from specialized professionals, also offering the advantage of impartial evaluation. Moreover, a significant portion of students in Brazil presents literacy difficulties associated with reading skills and lacks adequate assistance and diagnosis for conditions such as dyslexia. This research line aims to encompass research projects at the intersection of health, education, and artificial intelligence. The studies seek to investigate tools for assessing oral reading through innovative technologies, which can be used by health professionals in collaboration with educators. These tools aim to assist in identifying the level of reading development, factors influencing these skills, association with academic performance, early screening of signs of difficulties and disorders affecting reading fluency, differential diagnoses, as well as the appropriate medical/educational conduct. |
| Assessment and psychological interventions in mental health | This line of research concentrates studies related to mental health outcomes based on different theories and methods in Clinical Psychology. It aims at understanding psychological processes and building and adapting instruments and interventions with a psychotherapeutic and psychoeducational focus. |
| Psychosocial Processes: Practices and contexts | This line of research concentrates studies on psychosocial phenomena and vulnerability processes in different contexts, such as education, public health, work, politics and justice. It aims to develop strategies for assessment and intervention with individuals, groups and organizations based on theoretical-methodological approaches that articulate different perspectives from Social Psychology and other fields of knowledge. |
| Cognition, brain and behavior | This line of research focuses on basic and applied studies of cognition and its behavioral and neurobiological implications. We seek to investigate neurocognitive and psychobiological processes and their relationship with behavior, development, learning and mental health. Research approaches involve theoretical and experimental models and instruments from neuropsychology, neurobiology and neuroscience. |
| Well-being, health and quality of life | This line of research concentrates studies that use an interdisciplinary approach on the relationship between mental health and lifestyle, understood as the set of behaviors related to food, physical activity, sleep, spirituality, financial well-being, well-being occupational and social relationships. The line aims at building basic and applied knowledge for evaluation and intervention in the prevention and promotion of quality of life and its different domains. |
| Obesity and Metabolic Syndrome | This line is concerned with research in the area of obesity and metabolic syndrome with consequences in co-morbidities involved or related to the aforementioned pathologies. |
| Epidemiological, Clinicopathological, Radiological and Molecular aspects of malignant neoplasms. | This area of concentration is intended to describe patients who suffer from malignant neoplasms in their different clinical stages, as well as to assess their clinical outcome by looking at the clinical, histopathological, radiological and molecular variables. Studies in this area may be accountable for addressing some issues that are still controversial among the scientific community. |
| Videolaparoscopic Surgery | This area of concentration is intended to assess the advantages of the procedures conducted using less invasive techniques. |
| COD | Workload | Description |
| 63416-02 | 30 | This course is intended to introduce students to the main theoretical and practical concepts of the area of molecular biology, applied to the health area, focusing on the main current scientific topics of molecular biology therapies. |
| No offer for current semester |
| Concentration area | Type | Required |
| Biochemical and Molecular Pharmacology | Master's | Not required |
| Biochemical and Molecular Pharmacology | Doctorate | Not required |
| Biomedical Gerontology | Master's | Not required |
| Biomedical Gerontology | Doctorate | Not required |
| CTBMF | Master's | Not required |
| CTBMF | Doctorate | Not required |
| Cellular and Molecular Biology | Master's | Not required |
| Clinical Psychology | Master's | Not required |
| Clinical Psychology | Doctorate | Not required |
| Clinical Stomatology | Master's | Not required |
| Clinical Stomatology | Doctorate | Not required |
| Dental Materials | Master's | Not required |
| Dental Materials | Doctorate | Not required |
| Dental Prosthetics | Master's | Not required |
| Dental Prosthetics | Doctorate | Not required |
| Endodontics | Master's | Not required |
| Endodontics | Doctorate | Not required |
| Human Cognition | Master's | Not required |
| Human Cognition | Doctorate | Not required |
| Medical Practice | Master's | Not required |
| Medical Practice | Doctorate | Not required |
| Nephrology | Master's | Not required |
| Nephrology | Doctorate | Not required |
| Neurosciences | Master's | Not required |
| Neurosciences | Doctorate | Not required |
| Orthodontics and Facial Orthopedics | Master's | Not required |
| Orthodontics and Facial Orthopedics | Doctorate | Not required |
| Pediatrics | Master's | Not required |
| Pediatrics | Doctorate | Not required |
| Psychology | Doctorate | Not required |
| Restorative Dentistry | Master's | Not required |
| Restorative Dentistry | Doctorate | Not required |
| Social Psychology | Master's | Not required |
| Social Psychology | Doctorate | Not required |
| Surgical Practice | Master's | Not required |
| Surgical Practice | Doctorate | Not required |
| Research line | Description |
| Evaluation of mechanisms involved in inflammatory and nociceptive alterations | This line of research is concerned with the evaluation of mechanisms involved in inflammatory and nociceptive alterations |
| Drug Development | This line of research has been designed for the development of drugs against neglected tropical diseases (tuberculosis and malaria) and the development of drugs against chronic and degenerative diseases. |
| Evaluation of pharmacological targets in cancer treatment | This line of research is concerned with the evaluation of pharmacological targets in cancer treatment and inflammation. |
| Analysis and evaluation of neurochemical and pharmacological mechanisms in neurological diseases | Study of the neurochemical roots and pharmacological targets in neurological diseases. |
| Biological Aspects of Aging | This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo). |
| Clinical and Emotional Aspects of Aging | This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition. |
| Social-cultural, Demographic and Bioethical Aspects of Aging | This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging. |
| Aging and Public Health | This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life. |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| Extra-renal dialysis and transplatation | This line of research is intended for the study of different modalities of renal replacement therapies, with emphasis on organ transplantation, especially when it comes to immunology of transplants. |
| Clinical nephrology and arterial hypertension | This line of research will address topics related to several aspects of clinical nephrology, renal function, arterial hypertension, renal and metabolic diseases. |
| Molecular Biology, immunology and stem cell | This line of research is concerned with the study of molecular alterations in tumors, mainly those affecting the digestive and respiratory systems, through PCR techniques in real time, immunohistochemistry, flow cytometry and cell cultivation. It will also look at Cell Therapy and Tissue Engineering. |
| Cardiology/Risk Factors and genetics factors in cardiovascular diseases | This line of research is concerned with assessing risk factors for cardiovascular surgeries using markers; traditional risk factors (dyslipidemias, arterial hypertension, diabetes, smoke addiction) and potential emerging ones (apolipoprotein B,small and dense LDL cholesterol) in coronary heart diseases. |
| Cardiology/Cellular therapy | This line of research is intended to assess the efficiency and safety of autologous implants of bone marrow stem cells in patients suffering from dilated cardiomyopathy and in patients suffering from acute myocardial infarction. |
| Cellular metabolism and membrane transport in renal and metabolic diseases (or disease states) | This line of research is designed for the study of physiopathogenic mechanisms of several renal and metabolic diseases. |
| Training and Faculty Development in Health | |
| Study abdomen adult and elderly healthy and sick with new technologies in Diagnostic Imaging | First of all, this line of research is intended to introduce students to different abdominal organs in advanced imaging modalities, such as magnetic resonance and positron emission tomography. It is intended to study the normal anatomy of these organs and tissues and their anatomic variations, thus allowing for a comparison between healthy and unhealthy individuals. With this, we intent to provide deeper insights into the abdomen's normal anatomy and its anatomic variation through new imaging technologies. Additionally, this line of research will determine the diagnostic imaging accuracy of gastrointestinal tract and urinary system diseases. We are intent on reaching an earlier and more precise diagnosis of the diseases of adult and elderly patients, thus increasing their survival. It has been designed to produce researchers and professors who want to work within this line of research responsible for studying the most common diseases in our population. |
| Clinical Epidemiology | This area of concentration is intended to develop research in clinical epidemiology focusing on its methodological and clinical aspects. This line of research intends to encourage the development of research projects that contribute to the progress in identification, intervention and promotion of determinants of the health-disease process in human population. |
| Functional and Molecular Image of the Body | Functional imaging is the state-of-the-art in diagnostic imaging. Magnetic Resonance made a giant leap in that direction through the employment of ultra-rapid acquisition techniques, which have enabled the measurement of variations in oxygen consumption levels arising from the BOLD effect and an estimation of the cellularity of tissues through the diffusion technique. PET has enabled Nuclear Medicine to measure the level of consumption of glucose in the tissue, by making use of ionizing radiation. It is largely employed in the investigation of tumors and metastasis, which have naturally increased the consumption of glucose due to a larger metabolic level. More recently, the Dynamic PET has enabled the assessment of the consumption of glucose over time and the measurement of the most active regions more precisely. |
| Epidemiology and Environmental Health | This course is intended to encourage the development of research into the area of epidemiology and environmental health with an eye to the methodological and clinical aspects. This line of research seeks to encourage the development of research projects that contribute to the advancement of the identification, intervention and promotion of the determinants of the health-disease process in human population. |
| Technological Innovations in the Health Area | Curently, we are seeing worldwide the fast development of technologies, proceedings and medicines focus at the most effective treatment of diseases and the restoration of health. This accelerated step with which medical knowledge progresses makes it necessary to create a new mentality in medical training, stimulating curiosity, the active search for knowledge and constant updating. The number and complexity of the scientific processes that lead to this evolution are also worthy of attention, both due to the need for training to understand them, as well as the work opportunity they represent for doctors in general. |
| Neurology/ stem cells | This line of research is concerned with the assessment of the possibility of regeneration of central and peripheral neurological injuries resulting from neurodegenerative diseases, with somatic stem cells, as well as with the study of the structural and functional mechanisms of regeneration from injuries. |
| Behavioral neurology and neuropsychiatry | This line of research will look at the neurobiology of psychiatric diseases and behavioral alterations in major neurological diseases. |
| Cognitive brain imaging | This line of research will look at the development of new techniques for the analysis of neuroimaging and studies of neural bases of superior cognitive processes (for instance, language comprehension and acquisition, executive functions, spatial reasoning). |
| Neurotoxic activity of ureases and derived peptides | This line of research will address the neurotoxic and pro-inflammatory activities of ureases of different organisms. It will also address the methodologies of study of neurotoxicity relying on the use of insects-models. As well as this, it will look at ureases as virulence factors for pathogenic microorganisms, especially bacteria Helicobacter pylori and Proteus mirabilis and Cryptococcu yeasts. |
| Neuroinflammation/Multiple Sclerosis/ neuromyelitis optica | The inflammation resulting from neurological diseases may be primarily involved with the physiopathology of immunomediated diseases of the nervous system, such as multiple sclerosis, neuromyelitis optica, ADEM - acute demyelinating encephalomyelitis, Guillain-Barré syndrome, autoimmune encephalitis and some neurological complications resulting directly or indirectly from viral or bacterial infections (e.g. meningoencephalitis). In other diseases, the inflammation plays a major role, but less clear than it is in strokes and in degenerative diseases of the central nervous system. The deregulation in the immune system, be it either temporary or permanent, may lead to injuries in the brain, bone marrow and peripheral nerves that cause permanent neuronal damage with the risk of aftereffects and permanent incapacity. By relying on advanced methods in molecular biology associated with clinical and imaging assessment (magnetic resonance, nuclear medicine), we have conducted research that is intended to understand the intrinsic and extrinsic mechanisms that lead to an increase of pro-inflammatory substances such as cytokines, chemokines, the production of autoantibodies, complement system activation, proliferation / maturation of autoreactive lymphocytes T and B, microglial activation and the alteration of the blood-brain barrier. Besides, we have conducted research for the identification of specific biomarkers for each disease which may assist in the establishment of better diagnosis/prognosis and in experimental animal models for the study of physiopathology and innovative therapeutic interventions. |
| Epilepsy | This line of research will cover clinical and electroencephalographic, pharmacological, neuroimaging and surgical studies in the realm of epilepsy. The direct involvement of São Lucas Hospital with the diagnosis, clinical treatment and epilepsy surgery opens interesting perspectives of investigation, seeking diagnostic refinement, new treatment options and the correlations of epileptic syndromes with structural alterations of the brain. |
| The central nervous system (CNS) formation stages can be considered a great concert with the regency of different signaling molecules that trigger a cascade of dependent and complementary processes until the formation of all CNS structures as well as their different functionalities. The human brain is a puzzle of more than 100 billion pieces that must be accurately directed to its unique and specific location. The studies of Molecurar Bases of Embryonic Neurogenesis presents a comprehensive view of understanding the CNS, from its embryonic formation to neurogenesis in the adult brain, guiding clinical and pathological situations related to cerebral malformations and new therapeutic alternatives for CNS recovery. The use of molecular techniques as next-generation sequencing (NGS), super arrays, relative expression, genotyping, etc., are used to describe signaling pathways, genesis of pathologies, and application of precision medicine for the treatment of various diseases. The cell reprogramming at the embryonic level through the generation of induced pluripotent stem cells (iPSC) helps to understand embryonic neurogenesis and screening of new drugs for the treatment of alterations during the formation of the central nervous system and its associated pathologies | |
| Artificial Intelligence in Healthcare | Fluency in oral reading is a crucial skill for children and adolescents, involving the ability to read a text with accuracy, appropriate expression, and at a determined pace. Artificial intelligence has enabled considerable advances in activities that previously required time and attention from specialized professionals, also offering the advantage of impartial evaluation. Moreover, a significant portion of students in Brazil presents literacy difficulties associated with reading skills and lacks adequate assistance and diagnosis for conditions such as dyslexia. This research line aims to encompass research projects at the intersection of health, education, and artificial intelligence. The studies seek to investigate tools for assessing oral reading through innovative technologies, which can be used by health professionals in collaboration with educators. These tools aim to assist in identifying the level of reading development, factors influencing these skills, association with academic performance, early screening of signs of difficulties and disorders affecting reading fluency, differential diagnoses, as well as the appropriate medical/educational conduct. |
| Assessment and psychological interventions in mental health | This line of research concentrates studies related to mental health outcomes based on different theories and methods in Clinical Psychology. It aims at understanding psychological processes and building and adapting instruments and interventions with a psychotherapeutic and psychoeducational focus. |
| Psychosocial Processes: Practices and contexts | This line of research concentrates studies on psychosocial phenomena and vulnerability processes in different contexts, such as education, public health, work, politics and justice. It aims to develop strategies for assessment and intervention with individuals, groups and organizations based on theoretical-methodological approaches that articulate different perspectives from Social Psychology and other fields of knowledge. |
| Cognition, brain and behavior | This line of research focuses on basic and applied studies of cognition and its behavioral and neurobiological implications. We seek to investigate neurocognitive and psychobiological processes and their relationship with behavior, development, learning and mental health. Research approaches involve theoretical and experimental models and instruments from neuropsychology, neurobiology and neuroscience. |
| Well-being, health and quality of life | This line of research concentrates studies that use an interdisciplinary approach on the relationship between mental health and lifestyle, understood as the set of behaviors related to food, physical activity, sleep, spirituality, financial well-being, well-being occupational and social relationships. The line aims at building basic and applied knowledge for evaluation and intervention in the prevention and promotion of quality of life and its different domains. |
| Obesity and Metabolic Syndrome | This line is concerned with research in the area of obesity and metabolic syndrome with consequences in co-morbidities involved or related to the aforementioned pathologies. |
| Epidemiological, Clinicopathological, Radiological and Molecular aspects of malignant neoplasms. | This area of concentration is intended to describe patients who suffer from malignant neoplasms in their different clinical stages, as well as to assess their clinical outcome by looking at the clinical, histopathological, radiological and molecular variables. Studies in this area may be accountable for addressing some issues that are still controversial among the scientific community. |
| Videolaparoscopic Surgery | This area of concentration is intended to assess the advantages of the procedures conducted using less invasive techniques. |
| COD | Workload | Description |
| 196UA-02 | 30 | To cover basic and advanced aspects of neuroimmunoendocrine interactions in health and disease. Introduce the neural, hormonal, and cellular pathways involved in the neuroimmunoendocrine communication. Discuss the impact of chronic stress and early trauma on the immune system. Discuss the role of cytokines in sickness behavior. Describe the role of inflammation in the etiology of mood disorders. Analyze the roles of the immune system in the development of the central nervous system. Present the role of leukocytes in complex human behavior (memory, social interaction). Explain the placebo effect and its neuroimmunoendocrine pathways. |
| No offer for current semester |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 73195-02 | 30 | This course is intended to enable students to understand and apply sample preparation techniques and quantitative analysis in microscopy for the different areas of biological and biomedical sciences. |
| No offer for current semester |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 73177-04 | 60 | This course will cover the following topics: Scientific writing in English. Structure, language and strategies for production of scientific papers. The process of paper submission and response to reviewers. Techniques for oral presentation of scientific papers in English. |
| No offer for current semester |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 13157-02 | 30 | To follow are the topics this course will address: The determination of protein-ligand interactions. Types of interactions. Analytical methods for supramolecular studies. Quantitative methods of bond energies. |
| Professors | Home time | Lattes |
| PABLO MACHADO | 12 years and 9 months | Link |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 7311B-02 | 30 | This course intends to foster discussions on research policies in Brazil, including the assessment criteria employed by CAPES as well as scientometrics criteria. It also discusses the means for obtaining funding for scientific projects with an eye to meeting the different criteria set forth in specific projects. Additionally, one of the goals of the course is to discuss the scientific career both in Brazil and overseas and the possibilities for getting into the market. The course will discuss the differences between the areas of concentration as well as regional differences and other controversial topics in science. The peer-review process will be addressed, for both projects and scientific papers submitted to indexed journals. Part of the classes will be devoted for discussions on the ethical aspects of research, including issues such as plagiarism, co-authorship, publication of negative results, among others. Students will receive specific training to properly advise final papers as well as theses and dissertations. |
| No offer for current semester |
| Concentration area | Type | Required |
| Biochemical and Molecular Pharmacology | Master's | Not required |
| Biochemical and Molecular Pharmacology | Doctorate | Not required |
| Biomedical Gerontology | Master's | Not required |
| Biomedical Gerontology | Doctorate | Not required |
| CTBMF | Master's | Not required |
| CTBMF | Doctorate | Not required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Clinical Psychology | Master's | Not required |
| Clinical Psychology | Doctorate | Not required |
| Clinical Stomatology | Master's | Not required |
| Clinical Stomatology | Doctorate | Not required |
| Dental Materials | Master's | Not required |
| Dental Materials | Doctorate | Not required |
| Dental Prosthetics | Master's | Not required |
| Dental Prosthetics | Doctorate | Not required |
| Ecology and Evolution of Biodiversity | Master's | Not required |
| Ecology and Evolution of Biodiversity | Doctorate | Not required |
| Endodontics | Master's | Not required |
| Endodontics | Doctorate | Not required |
| Human Cognition | Master's | Not required |
| Human Cognition | Doctorate | Not required |
| Medical Practice | Master's | Not required |
| Medical Practice | Doctorate | Not required |
| Nephrology | Master's | Not required |
| Nephrology | Doctorate | Not required |
| Neurosciences | Master's | Not required |
| Neurosciences | Doctorate | Not required |
| Orthodontics and Facial Orthopedics | Master's | Not required |
| Orthodontics and Facial Orthopedics | Doctorate | Not required |
| Pediatrics | Master's | Not required |
| Pediatrics | Doctorate | Not required |
| Psychology | Doctorate | Not required |
| Restorative Dentistry | Master's | Not required |
| Restorative Dentistry | Doctorate | Not required |
| Social Psychology | Master's | Not required |
| Social Psychology | Doctorate | Not required |
| Surgical Practice | Master's | Not required |
| Surgical Practice | Doctorate | Not required |
| Research line | Description |
| Evaluation of mechanisms involved in inflammatory and nociceptive alterations | This line of research is concerned with the evaluation of mechanisms involved in inflammatory and nociceptive alterations |
| Drug Development | This line of research has been designed for the development of drugs against neglected tropical diseases (tuberculosis and malaria) and the development of drugs against chronic and degenerative diseases. |
| Evaluation of pharmacological targets in cancer treatment | This line of research is concerned with the evaluation of pharmacological targets in cancer treatment and inflammation. |
| Analysis and evaluation of neurochemical and pharmacological mechanisms in neurological diseases | Study of the neurochemical roots and pharmacological targets in neurological diseases. |
| Biological Aspects of Aging | This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo). |
| Clinical and Emotional Aspects of Aging | This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition. |
| Social-cultural, Demographic and Bioethical Aspects of Aging | This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging. |
| Aging and Public Health | This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life. |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| Ecology and Conservation | This line of research encompasses projects focusing on ecological relationships among organisms and with their environment, including studies of autecology, ecophysiology, behavior, population dynamics and community ecology, as well as projects aiming to provide scientific bases for biodiversity conservation strategies. |
| Systematics and Evolution | The research line brings together projects related to the evolution of biodiversity, including studies in phylogenetic systematics (using morphological and molecular data, including phylogenomics), taxonomy, comparative morphology, biogeography, evolutionary genetics, and comparative genomics. |
| The research line brings together projects focused on the use of large amounts of information ('big data') and the development of innovative data mining and analysis methodologies (e.g., employing machine learning) to investigate issues related to the characterization, monitoring, and conservation of biodiversity | |
| The research line encompasses projects aimed at applying ecological data, biodiversity component analyses, and/or interdisciplinary studies to solve problems with more direct socio-environmental and/or economic impact. This includes studies in the fields of ecotoxicology and environmental microbiology with a focus on the characterization, monitoring, and mitigation of environmental impacts, as well as the development of more sustainable agricultural methods using components of Brazil's native biodiversity. It also includes projects aimed at developing innovative products from biodiversity sources and/or integrating biodiversity analyses into regional economic development models with a focus on environmental sustainability. | |
| Extra-renal dialysis and transplatation | This line of research is intended for the study of different modalities of renal replacement therapies, with emphasis on organ transplantation, especially when it comes to immunology of transplants. |
| Clinical nephrology and arterial hypertension | This line of research will address topics related to several aspects of clinical nephrology, renal function, arterial hypertension, renal and metabolic diseases. |
| Molecular Biology, immunology and stem cell | This line of research is concerned with the study of molecular alterations in tumors, mainly those affecting the digestive and respiratory systems, through PCR techniques in real time, immunohistochemistry, flow cytometry and cell cultivation. It will also look at Cell Therapy and Tissue Engineering. |
| Cardiology/Risk Factors and genetics factors in cardiovascular diseases | This line of research is concerned with assessing risk factors for cardiovascular surgeries using markers; traditional risk factors (dyslipidemias, arterial hypertension, diabetes, smoke addiction) and potential emerging ones (apolipoprotein B,small and dense LDL cholesterol) in coronary heart diseases. |
| Cardiology/Cellular therapy | This line of research is intended to assess the efficiency and safety of autologous implants of bone marrow stem cells in patients suffering from dilated cardiomyopathy and in patients suffering from acute myocardial infarction. |
| Cellular metabolism and membrane transport in renal and metabolic diseases (or disease states) | This line of research is designed for the study of physiopathogenic mechanisms of several renal and metabolic diseases. |
| Training and Faculty Development in Health | |
| Study abdomen adult and elderly healthy and sick with new technologies in Diagnostic Imaging | First of all, this line of research is intended to introduce students to different abdominal organs in advanced imaging modalities, such as magnetic resonance and positron emission tomography. It is intended to study the normal anatomy of these organs and tissues and their anatomic variations, thus allowing for a comparison between healthy and unhealthy individuals. With this, we intent to provide deeper insights into the abdomen's normal anatomy and its anatomic variation through new imaging technologies. Additionally, this line of research will determine the diagnostic imaging accuracy of gastrointestinal tract and urinary system diseases. We are intent on reaching an earlier and more precise diagnosis of the diseases of adult and elderly patients, thus increasing their survival. It has been designed to produce researchers and professors who want to work within this line of research responsible for studying the most common diseases in our population. |
| Clinical Epidemiology | This area of concentration is intended to develop research in clinical epidemiology focusing on its methodological and clinical aspects. This line of research intends to encourage the development of research projects that contribute to the progress in identification, intervention and promotion of determinants of the health-disease process in human population. |
| Functional and Molecular Image of the Body | Functional imaging is the state-of-the-art in diagnostic imaging. Magnetic Resonance made a giant leap in that direction through the employment of ultra-rapid acquisition techniques, which have enabled the measurement of variations in oxygen consumption levels arising from the BOLD effect and an estimation of the cellularity of tissues through the diffusion technique. PET has enabled Nuclear Medicine to measure the level of consumption of glucose in the tissue, by making use of ionizing radiation. It is largely employed in the investigation of tumors and metastasis, which have naturally increased the consumption of glucose due to a larger metabolic level. More recently, the Dynamic PET has enabled the assessment of the consumption of glucose over time and the measurement of the most active regions more precisely. |
| Epidemiology and Environmental Health | This course is intended to encourage the development of research into the area of epidemiology and environmental health with an eye to the methodological and clinical aspects. This line of research seeks to encourage the development of research projects that contribute to the advancement of the identification, intervention and promotion of the determinants of the health-disease process in human population. |
| Technological Innovations in the Health Area | Curently, we are seeing worldwide the fast development of technologies, proceedings and medicines focus at the most effective treatment of diseases and the restoration of health. This accelerated step with which medical knowledge progresses makes it necessary to create a new mentality in medical training, stimulating curiosity, the active search for knowledge and constant updating. The number and complexity of the scientific processes that lead to this evolution are also worthy of attention, both due to the need for training to understand them, as well as the work opportunity they represent for doctors in general. |
| Neurology/ stem cells | This line of research is concerned with the assessment of the possibility of regeneration of central and peripheral neurological injuries resulting from neurodegenerative diseases, with somatic stem cells, as well as with the study of the structural and functional mechanisms of regeneration from injuries. |
| Behavioral neurology and neuropsychiatry | This line of research will look at the neurobiology of psychiatric diseases and behavioral alterations in major neurological diseases. |
| Cognitive brain imaging | This line of research will look at the development of new techniques for the analysis of neuroimaging and studies of neural bases of superior cognitive processes (for instance, language comprehension and acquisition, executive functions, spatial reasoning). |
| Neurotoxic activity of ureases and derived peptides | This line of research will address the neurotoxic and pro-inflammatory activities of ureases of different organisms. It will also address the methodologies of study of neurotoxicity relying on the use of insects-models. As well as this, it will look at ureases as virulence factors for pathogenic microorganisms, especially bacteria Helicobacter pylori and Proteus mirabilis and Cryptococcu yeasts. |
| Neuroinflammation/Multiple Sclerosis/ neuromyelitis optica | The inflammation resulting from neurological diseases may be primarily involved with the physiopathology of immunomediated diseases of the nervous system, such as multiple sclerosis, neuromyelitis optica, ADEM - acute demyelinating encephalomyelitis, Guillain-Barré syndrome, autoimmune encephalitis and some neurological complications resulting directly or indirectly from viral or bacterial infections (e.g. meningoencephalitis). In other diseases, the inflammation plays a major role, but less clear than it is in strokes and in degenerative diseases of the central nervous system. The deregulation in the immune system, be it either temporary or permanent, may lead to injuries in the brain, bone marrow and peripheral nerves that cause permanent neuronal damage with the risk of aftereffects and permanent incapacity. By relying on advanced methods in molecular biology associated with clinical and imaging assessment (magnetic resonance, nuclear medicine), we have conducted research that is intended to understand the intrinsic and extrinsic mechanisms that lead to an increase of pro-inflammatory substances such as cytokines, chemokines, the production of autoantibodies, complement system activation, proliferation / maturation of autoreactive lymphocytes T and B, microglial activation and the alteration of the blood-brain barrier. Besides, we have conducted research for the identification of specific biomarkers for each disease which may assist in the establishment of better diagnosis/prognosis and in experimental animal models for the study of physiopathology and innovative therapeutic interventions. |
| Epilepsy | This line of research will cover clinical and electroencephalographic, pharmacological, neuroimaging and surgical studies in the realm of epilepsy. The direct involvement of São Lucas Hospital with the diagnosis, clinical treatment and epilepsy surgery opens interesting perspectives of investigation, seeking diagnostic refinement, new treatment options and the correlations of epileptic syndromes with structural alterations of the brain. |
| The central nervous system (CNS) formation stages can be considered a great concert with the regency of different signaling molecules that trigger a cascade of dependent and complementary processes until the formation of all CNS structures as well as their different functionalities. The human brain is a puzzle of more than 100 billion pieces that must be accurately directed to its unique and specific location. The studies of Molecurar Bases of Embryonic Neurogenesis presents a comprehensive view of understanding the CNS, from its embryonic formation to neurogenesis in the adult brain, guiding clinical and pathological situations related to cerebral malformations and new therapeutic alternatives for CNS recovery. The use of molecular techniques as next-generation sequencing (NGS), super arrays, relative expression, genotyping, etc., are used to describe signaling pathways, genesis of pathologies, and application of precision medicine for the treatment of various diseases. The cell reprogramming at the embryonic level through the generation of induced pluripotent stem cells (iPSC) helps to understand embryonic neurogenesis and screening of new drugs for the treatment of alterations during the formation of the central nervous system and its associated pathologies | |
| Artificial Intelligence in Healthcare | Fluency in oral reading is a crucial skill for children and adolescents, involving the ability to read a text with accuracy, appropriate expression, and at a determined pace. Artificial intelligence has enabled considerable advances in activities that previously required time and attention from specialized professionals, also offering the advantage of impartial evaluation. Moreover, a significant portion of students in Brazil presents literacy difficulties associated with reading skills and lacks adequate assistance and diagnosis for conditions such as dyslexia. This research line aims to encompass research projects at the intersection of health, education, and artificial intelligence. The studies seek to investigate tools for assessing oral reading through innovative technologies, which can be used by health professionals in collaboration with educators. These tools aim to assist in identifying the level of reading development, factors influencing these skills, association with academic performance, early screening of signs of difficulties and disorders affecting reading fluency, differential diagnoses, as well as the appropriate medical/educational conduct. |
| Assessment and psychological interventions in mental health | This line of research concentrates studies related to mental health outcomes based on different theories and methods in Clinical Psychology. It aims at understanding psychological processes and building and adapting instruments and interventions with a psychotherapeutic and psychoeducational focus. |
| Psychosocial Processes: Practices and contexts | This line of research concentrates studies on psychosocial phenomena and vulnerability processes in different contexts, such as education, public health, work, politics and justice. It aims to develop strategies for assessment and intervention with individuals, groups and organizations based on theoretical-methodological approaches that articulate different perspectives from Social Psychology and other fields of knowledge. |
| Cognition, brain and behavior | This line of research focuses on basic and applied studies of cognition and its behavioral and neurobiological implications. We seek to investigate neurocognitive and psychobiological processes and their relationship with behavior, development, learning and mental health. Research approaches involve theoretical and experimental models and instruments from neuropsychology, neurobiology and neuroscience. |
| Well-being, health and quality of life | This line of research concentrates studies that use an interdisciplinary approach on the relationship between mental health and lifestyle, understood as the set of behaviors related to food, physical activity, sleep, spirituality, financial well-being, well-being occupational and social relationships. The line aims at building basic and applied knowledge for evaluation and intervention in the prevention and promotion of quality of life and its different domains. |
| Obesity and Metabolic Syndrome | This line is concerned with research in the area of obesity and metabolic syndrome with consequences in co-morbidities involved or related to the aforementioned pathologies. |
| Epidemiological, Clinicopathological, Radiological and Molecular aspects of malignant neoplasms. | This area of concentration is intended to describe patients who suffer from malignant neoplasms in their different clinical stages, as well as to assess their clinical outcome by looking at the clinical, histopathological, radiological and molecular variables. Studies in this area may be accountable for addressing some issues that are still controversial among the scientific community. |
| Videolaparoscopic Surgery | This area of concentration is intended to assess the advantages of the procedures conducted using less invasive techniques. |
| COD | Workload | Description |
| 196J2-02 | 30 | Study of the analytical and interpretative bases of research in molecular, cellular, and animal models using a translational approach. The subject applies critical-scientific reasoning to combine the production of pure and applied knowledge, with a focus on one health concept (animal-human-environmental interaction). The following issues are addressed: concepts of translational research; interface between pure and applied research; one health basis; classic study designs and analytical methods of translational scientific research. Study of the interpretative and application bases of scientific research in molecular, cellular, animal models and humans, from a translational and clinical perspective. Skeptical and critical-scientific reflection is used to bring together the production of pure and applied knowledge, focusing on one health concept (animal-human-environmental interaction). The following points are addressed: concepts of pure and applied research, translational research; interface between pure and applied research; and classical analytical designs and methods of scientific research in the biomedical and health areas. |
| No offer for current semester |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 196EI-02 | 30 | Basic and advanced theoretical concepts on current immunological strategies to combat COVID-19. Humoral and cellular immune responses, generation of immunological memory against SARS-COV-2 and its variants. Design and use of different types of vaccines, convalescent plasma, monoclonal antibodies and immunotherapies. Strategies focused on immunocompetent and immunosuppressed or immunosenescence individuals. |
| No offer for current semester |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |
| COD | Workload | Description |
| 196RL-01 | 15 |
| Professors | Home time | Lattes |
| FERNANDA BUENO MORRONE | 24 years and 9 months | Link |
| Concentration area | Type | Required |
| Cellular and Molecular Biology | Master's | Not required |
| Cellular and Molecular Biology | Doctorate | Not required |
| Research line | Description |
| Cell Structure and Metabolism | To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action. |
| Cellular and Molecular Immunology | To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts. |
| Cellular and Molecular Characterization in Microbiology and Parasitology | To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents. |
| Genetics, Genomics and Bioinformatics | To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics. |
| Cellular and Molecular Neurobiology | To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels. |
| Molecular Biology in the Drug/Target Interaction | To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer. |